Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | MMP13 | P45452 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | QPCT | Q16769 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29353662 | 0.89 | NPC1 (0.67) | NPC1RAB9AL3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL17834016 | 0.87 | RAB9A (0.48) | NPC1RAB9AL3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL17834031 | 0.87 | THRB (0.54) | NPC1RAB9AL3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL17825313 | 0.86 | RAB9A (0.54) | NPC1RAB9AL3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL17834025 | 0.86 | CYP19A1 (0.44) | NPC1RAB9AL3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL17834018 | 0.85 | KMT2A (0.56) | NPC1RAB9AL3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL17834021 | 0.84 | KMT2A (0.58) | NPC1RAB9AL3MBTL1SMN1; SMN2MMP13 | |
| SCHEMBL17834027 | 0.84 | LMNA (0.53) | NPC1RAB9AL3MBTL1SMN1; SMN2ALDH1A1 | |
| SCHEMBL17834026 | 0.84 | RAB9A (0.61) | NPC1RAB9AL3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL17834019 | 0.82 | ESR1 (0.47) | NPC1RAB9AL3MBTL1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016091228-A1 | SUBSTITUTED PHENYLTETRAZOLE, ITS USE AND PHARMACEUTICAL PREPARATION CONTAINING IT | UNIVERZITA KARLOVA V PRAZE (CZ) | 2016-06-16 | — | — | WO | disclosed |