Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.42 |
| ▸ | CCR2 | P41597 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17834018 | 0.89 | KMT2A (0.56) | ESR1KMT2ARAB9AL3MBTL1SMN1; SMN2 | |
| SCHEMBL17834016 | 0.89 | RAB9A (0.48) | KMT2ARAB9AL3MBTL1SMN1; SMN2NPC1 | |
| SCHEMBL17825313 | 0.85 | RAB9A (0.54) | KMT2ARAB9AL3MBTL1SMN1; SMN2NPC1 | |
| SCHEMBL17834021 | 0.85 | KMT2A (0.58) | KMT2ARAB9AL3MBTL1SMN1; SMN2NPC1 | |
| SCHEMBL17834027 | 0.85 | LMNA (0.53) | KMT2ARAB9AL3MBTL1SMN1; SMN2NPC1 | |
| SCHEMBL17834026 | 0.85 | RAB9A (0.61) | KMT2ARAB9AL3MBTL1SMN1; SMN2NPC1 | |
| SCHEMBL17825079 | 0.84 | RAB9A (0.48) | KMT2ARAB9AL3MBTL1SMN1; SMN2NPC1 | |
| SCHEMBL17834025 | 0.84 | CYP19A1 (0.44) | KMT2ARAB9AL3MBTL1SMN1; SMN2NPC1 | |
| SCHEMBL17834022 | 0.84 | KMT2A (0.47) | KMT2ARAB9AL3MBTL1SMN1; SMN2NPC1 | |
| SCHEMBL17834017 | 0.82 | NPC1 (0.58) | RAB9AL3MBTL1SMN1; SMN2NPC1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016091228-A1 | SUBSTITUTED PHENYLTETRAZOLE, ITS USE AND PHARMACEUTICAL PREPARATION CONTAINING IT | UNIVERZITA KARLOVA V PRAZE (CZ) | 2016-06-16 | — | — | WO | disclosed |