SCHEMBL1782552

SCHEMBL1782552

CC(C)CCC=CCC=O

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 2/20 0.35
CNR1 P21554 6/20 0.34
HIF1A Q16665 2/20 0.33
EPAS1 Q99814 2/20 0.33
FAAH O00519 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1782551 1.00 TRPV1 (0.35) TRPV1CNR1HIF1AEPAS1FAAH
SCHEMBL1783572 0.86 TRPV1 (0.42) TRPV1CNR1HIF1AEPAS1FAAH
SCHEMBL1783571 0.86 TRPV1 (0.42) TRPV1CNR1HIF1AEPAS1FAAH
SCHEMBL1782698 0.84 HIF1A (0.47) TRPV1CNR1HIF1AEPAS1FAAH
SCHEMBL1782696 0.84 HIF1A (0.47) TRPV1CNR1HIF1AEPAS1FAAH
SCHEMBL9748433 0.82 FAAH (0.36) TRPV1HIF1AEPAS1FAAH
SCHEMBL2840987 0.81 LMNA (0.35)
SCHEMBL1784792 0.79 TRPV1 (0.36) TRPV1CNR1FAAH
SCHEMBL1784790 0.79 TRPV1 (0.36) TRPV1CNR1FAAH
SCHEMBL1783867 0.78 TRPV1 (0.39) TRPV1CNR1FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8632792-B2 Cooling sensation agent composition and sensory stimulation agent composition TAKASAGO INTERNATIONAL CORPORATION (JP) 2014-01-21 US disclosed
US-20110117147-A1 COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION TAKASAGO INTERNATIONAL CORPORATION (JP) 2011-05-19 US disclosed
WO-2009123355-A2 COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION TAKASAGO INTERNATIONAL CORPORATION (JP) 2009-10-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110117147-A1 COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION TRPA1, HRH1, HRH2 TRPV1 8/4885CNR1 103/4885HIF1A 1980/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.