Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 3/20 | 0.47 |
| ▸ | EPAS1 | Q99814 | 3/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 2/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1782696 | 1.00 | HIF1A (0.47) | HIF1AEPAS1TRPV1CNR1FAAH | |
| SCHEMBL1783572 | 0.93 | TRPV1 (0.42) | HIF1AEPAS1TRPV1CNR1FAAH | |
| SCHEMBL1783571 | 0.93 | TRPV1 (0.42) | HIF1AEPAS1TRPV1CNR1FAAH | |
| SCHEMBL29291067 | 0.84 | TRPV1 (0.58) | HIF1AEPAS1TRPV1CNR1FAAH | |
| SCHEMBL1782551 | 0.84 | TRPV1 (0.35) | HIF1AEPAS1TRPV1CNR1FAAH | |
| SCHEMBL1782552 | 0.84 | TRPV1 (0.35) | HIF1AEPAS1TRPV1CNR1FAAH | |
| SCHEMBL28831520 | 0.81 | LMNA (0.48) | HIF1AEPAS1TRPV1CNR1FAAH | |
| SCHEMBL29453513 | 0.81 | LMNA (0.48) | HIF1AEPAS1TRPV1CNR1FAAH | |
| SCHEMBL1409410 | 0.79 | — | — | |
| SCHEMBL4453452 | 0.78 | ALDH1A1 (0.48) | TRPV1CNR1TRPM8LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8632792-B2 | Cooling sensation agent composition and sensory stimulation agent composition | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2014-01-21 | — | — | US | disclosed |
| US-20110117147-A1 | COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2011-05-19 | — | — | US | disclosed |
| WO-2009123355-A2 | COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2009-10-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110117147-A1 | COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION | TRPA1, HRH1, HRH2 | HIF1A 1980/4885EPAS1 3547/4885TRPV1 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.