Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRYAB | P02511 | 5/20 | 0.71 |
| ▸ | USP2 | O75604 | 2/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.71 |
| ▸ | MAPT | P10636 | 2/20 | 0.71 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.71 |
| ▸ | LMNA | P02545 | 1/20 | 0.71 |
| ▸ | CRYAA | P02489 | 1/20 | 0.69 |
| ▸ | PTGES | O14684 | 2/20 | 0.58 |
| ▸ | FNTA | P49354 | 2/20 | 0.52 |
| ▸ | FNTB | P49356 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Euphorbol SCHEMBL3231975 | 1.00 | CRYAB (0.71) | CRYABUSP2ALDH1A1CYP3A4MAPT | |
| Euphorbol SCHEMBL568715 | 1.00 | CRYAB (0.71) | CRYABUSP2ALDH1A1CYP3A4MAPT | |
| Euphorbol SCHEMBL4169147 | 1.00 | CRYAB (0.71) | CRYABUSP2ALDH1A1CYP3A4MAPT | |
| Euphorbol SCHEMBL28641448 | 1.00 | CRYAB (0.71) | CRYABUSP2ALDH1A1CYP3A4MAPT | |
| Euphorbol SCHEMBL4169151 | 1.00 | CRYAB (0.71) | CRYABUSP2ALDH1A1CYP3A4MAPT | |
| Euphorbol SCHEMBL7194852 | 1.00 | CRYAB (0.71) | CRYABUSP2ALDH1A1CYP3A4MAPT | |
| Eburicol SCHEMBL29398158 | 0.90 | CRYAB (0.57) | CRYABUSP2ALDH1A1CYP3A4MAPT | |
| Eburicoic Acid SCHEMBL24821085 | 0.90 | PTGES (0.71) | CRYABUSP2ALDH1A1CYP3A4MAPT | |
| Eburicoic Acid SCHEMBL24821079 | 0.90 | PTGES (0.71) | CRYABUSP2ALDH1A1CYP3A4MAPT | |
| Eburicoic Acid SCHEMBL24821073 | 0.90 | PTGES (0.71) | CRYABUSP2ALDH1A1CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250109096-A1 | ANTI-FUNGALS TARGETING THE SYNTHESIS OF FUNGAL SHINGOLIPIDS | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK | 2025-04-03 | — | — | US | disclosed |
| EP-3230259-B1 | ANTI-FUNGALS TARGETING THE SYNTHESIS OF FUNGAL SHINGOLIPIDS | UNIV NEW YORK STATE RES FOUND (US) | 2024-04-03 | — | — | EP | disclosed |
| US-20220298103-A1 | ANTI-FUNGALS TARGETING THE SYNTHESIS OF FUNGAL SHINGOLIPIDS | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2022-09-22 | — | — | US | disclosed |
| US-11390580-B2 | Anti-fungals targeting the synthesis of fungal shingolipids | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2022-07-19 | — | — | US | disclosed |
| US-20200062698-A1 | ANTI-FUNGALS TARGETING THE SYNTHESIS OF FUNGAL SHINGOLIPIDS | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2020-02-27 | — | — | US | disclosed |
| US-20180141897-A1 | ANTI-FUNGALS TARGETING THE SYNTHESIS OF FUNGAL SHINGOLIPIDS | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2018-05-24 | — | — | US | disclosed |
| EP-3230259-A1 | ANTI-FUNGALS TARGETING THE SYNTHESIS OF FUNGAL SHINGOLIPIDS | The Research Foundation for The State University of New York (US) | 2017-10-18 | — | — | EP | disclosed |
| WO-2016094307-A1 | ANTI-FUNGALS TARGETING THE SYNTHESIS OF FUNGAL SHINGOLIPIDS | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2016-06-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11390580-B2 | Anti-fungals targeting the synthesis of fungal shingolipids | LSS, ERG28, CYP51A1 | CRYAB 4683/4885USP2 3037/4885ALDH1A1 4312/4885 |
| US-20220298103-A1 | ANTI-FUNGALS TARGETING THE SYNTHESIS OF FUNGAL SHINGOLIPIDS | LSS, ERG28, CYP51A1 | CRYAB 4683/4885USP2 3037/4885ALDH1A1 4312/4885 |
| US-20180141897-A1 | ANTI-FUNGALS TARGETING THE SYNTHESIS OF FUNGAL SHINGOLIPIDS | LSS, ERG28, CYP51A1 | CRYAB 4683/4885USP2 3037/4885ALDH1A1 4312/4885 |
| US-20200062698-A1 | ANTI-FUNGALS TARGETING THE SYNTHESIS OF FUNGAL SHINGOLIPIDS | LSS, ERG28, CYP51A1 | CRYAB 4683/4885USP2 3037/4885ALDH1A1 4312/4885 |
| US-20250109096-A1 | ANTI-FUNGALS TARGETING THE SYNTHESIS OF FUNGAL SHINGOLIPIDS | LSS, ERG28, CYP51A1 | CRYAB 4683/4885USP2 3037/4885ALDH1A1 4312/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.