Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | UNG | P13051 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.42 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.41 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.41 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.38 |
| ▸ | ABAT | P80404 | 1/20 | 0.38 |
| ▸ | HNF4A | P41235 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30014296 | 1.00 | ALDH1A1 (0.48) | ALDH1A1UNGRAB9AKDM4EPTGS2 | |
| SCHEMBL436351 | 0.83 | ALDH1A1 (0.48) | ALDH1A1UNGRAB9AKDM4EPTGS2 | |
| SCHEMBL30589393 | 0.83 | ALDH1A1 (0.52) | ALDH1A1UNGRAB9AKDM4EPTGS2 | |
| SCHEMBL4613992 | 0.83 | ALDH1A1 (0.52) | ALDH1A1UNGRAB9AKDM4EPTGS2 | |
| SCHEMBL17825629 | 0.82 | ERN1 (0.42) | ALDH1A1UNGRAB9AKDM4EPTGS2 | |
| SCHEMBL1124850 | 0.79 | PTPN1 (0.65) | ALDH1A1UNGRAB9AKDM4EPTGS2 | |
| SCHEMBL1302677 | 0.79 | ERN1 (0.49) | ALDH1A1UNGRAB9AKDM4EPTGS2 | |
| SCHEMBL29953767 | 0.79 | CA12 (0.57) | ALDH1A1PTGS2PTPN1CYP1A2LCK | |
| SCHEMBL3388426 | 0.79 | CA12 (0.57) | ALDH1A1PTGS2PTPN1CYP1A2LCK | |
| SCHEMBL30253662 | 0.79 | ERN1 (0.49) | ALDH1A1UNGRAB9AKDM4EPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112619445-B | Novel Polymer-COF-MOF composite membrane and preparation method thereof | 苏州因安特新材料科技有限公司 | 2022-10-25 | — | — | CN | claimed |
| CN-112619445-A | Novel Polymer-COF-MOF composite film and preparation method thereof | 嘉兴罗顿新材料科技有限公司 | 2021-04-09 | — | — | CN | claimed |
| US-20230346752-A1 | PSMA BINDING LIGAND-LINKER CONJUGATES AND METHODS FOR USING | PURDUE RESEARCH FOUNDATION | 2023-11-02 | — | — | US | disclosed |
| US-20230293497-A1 | PSMA BINDING LIGAND-LINKER CONJUGATES AND METHODS FOR USING | PURDUE RESEARCH FOUNDATION (US) | 2023-09-21 | — | — | US | disclosed |
| US-11717514-B2 | PSMA binding ligand-linker conjugates and methods for using | PURDUE RESEARCH FOUNDATION (US) | 2023-08-08 | — | — | US | disclosed |
| CN-112619445-B | Novel Polymer-COF-MOF composite membrane and preparation method thereof | 苏州因安特新材料科技有限公司 | 2022-10-25 | — | — | CN | disclosed |
| CN-112619445-A | Novel Polymer-COF-MOF composite film and preparation method thereof | 嘉兴罗顿新材料科技有限公司 | 2021-04-09 | — | — | CN | disclosed |
| US-9951324-B2 | PSMA binding ligand-linker conjugates and methods for using | PURDUE RESEARCH FOUNDATION (US) | 2018-04-24 | — | — | US | disclosed |
| US-9782493-B2 | Conjugates for treating diseases caused by PSMA expressing cells | ENDOCYTE, INC. (US) | 2017-10-10 | — | — | US | disclosed |
| US-20170266303-A1 | METHODS OF TREATING CANCER BY TARGETING TUMOR-ASSOCIATED MACROPHAGES | PURDUE RESEARCH FOUNDATION | 2017-09-21 | — | — | US | disclosed |
| US-20170258932-A1 | CONJUGATES FOR TREATING DISEASES CAUSED BY PSMA EXPRESSING CELLS | ENDOCYTE INC (US) | 2017-09-14 | — | — | US | disclosed |
| US-20120022245-A1 | FOLATE TARGETING OF NUCLEOTIDES | PURDUE RESEARCH FOUNDATION (US) | 2012-01-26 | — | — | US | disclosed |
| US-20110288152-A1 | PSMA BINDING LIGAND-LINKER CONJUGATES AND METHODS FOR USING | PURDUE RESEARCH FOUNDATION (US) | 2011-11-24 | — | — | US | disclosed |
| US-20100324008-A1 | PSMA BINDING LIGAND-LINKER CONJUGATES AND METHODS FOR USING | PURDUE RESEARCH FOUNDATION (US) | 2010-12-23 | — | — | US | disclosed |
| US-20100323973-A1 | CONJUGATES CONTAINING HYDROPHILIC SPACER LINKERS | ENDOCTYE, INC. | 2010-12-23 | — | — | US | disclosed |
| US-6888010-B2 | Process for the preparation of 5-formylphthalide | INFOSINT SA (CH) | 2005-05-03 | — | — | US | disclosed |
| US-20040225136-A1 | Process for the preparation of 5-formylphthalide | H. LUNDBECK A/S (DK) | 2004-11-11 | — | — | US | disclosed |
| EP-1281708-B1 | Process for the preparation of 5-Formylphthalide | INFOSINT SA (CH) | 2004-05-26 | — | — | EP | disclosed |
| WO-2003011847-A1 | PROCESS FOR THE PREPARATION OF 5-FORMYLPHTHALIDE | INFOSINT SA (CH) | 2003-02-13 | — | — | WO | disclosed |
| EP-1281708-A1 | Process for the preparation of 5-Formylphthalide | INFOSINT SA (CH) | 2003-02-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230293497-A1 | PSMA BINDING LIGAND-LINKER CONJUGATES AND METHODS FOR USING | FOLH1, KLK3, PSMA1 | ALDH1A1 2843/4885UNG 2767/4885RAB9A 2483/4885 |
| US-20120022245-A1 | FOLATE TARGETING OF NUCLEOTIDES | FOLR1, FOLR2, DHFR | ALDH1A1 1932/4885UNG 142/4885RAB9A 3184/4885 |
| US-20110288152-A1 | PSMA BINDING LIGAND-LINKER CONJUGATES AND METHODS FOR USING | FOLH1, KLK3, PSMA1 | ALDH1A1 2290/4885UNG 1756/4885RAB9A 2335/4885 |
| US-20170266303-A1 | METHODS OF TREATING CANCER BY TARGETING TUMOR-ASSOCIATED MACROPHAGES | FOLR1, FOLR2, FOLH1 | ALDH1A1 1100/4885UNG 369/4885RAB9A 3482/4885 |
| US-20170258932-A1 | CONJUGATES FOR TREATING DISEASES CAUSED BY PSMA EXPRESSING CELLS | FOLH1, KLK3, CD47 | ALDH1A1 642/4885UNG 3143/4885RAB9A 1053/4885 |
| US-20100324008-A1 | PSMA BINDING LIGAND-LINKER CONJUGATES AND METHODS FOR USING | FOLH1, KLK3, PSMA1 | ALDH1A1 2843/4885UNG 2767/4885RAB9A 2483/4885 |
| US-11717514-B2 | PSMA binding ligand-linker conjugates and methods for using | FOLH1, KLK3, PSMA1 | ALDH1A1 2843/4885UNG 2767/4885RAB9A 2483/4885 |
| US-20100323973-A1 | CONJUGATES CONTAINING HYDROPHILIC SPACER LINKERS | CD44, HAVCR2, HCAR1 | ALDH1A1 2723/4885UNG 3216/4885RAB9A 2900/4885 |
| US-20230346752-A1 | PSMA BINDING LIGAND-LINKER CONJUGATES AND METHODS FOR USING | FOLH1, KLK3, PSMA1 | ALDH1A1 2843/4885UNG 2767/4885RAB9A 2483/4885 |
| US-20040225136-A1 | Process for the preparation of 5-formylphthalide | HTR5A, TPH1, HTR6 | ALDH1A1 490/4885UNG 949/4885RAB9A 4211/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.