Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12952231 | 0.97 | ADRB2 (0.32) | ALDH1A1TBXA2RCYP26B1PKMADRB2 | |
| SCHEMBL1656937 | 0.96 | ADRB2 (0.33) | ALDH1A1TBXA2RCYP26B1PKMADRB2 | |
| SCHEMBL559885 | 0.95 | ADRB2 (0.33) | ALDH1A1TBXA2RCYP26B1PKMADRB2 | |
| SCHEMBL559886 | 0.95 | ADRB2 (0.33) | ALDH1A1TBXA2RCYP26B1PKMADRB2 | |
| SCHEMBL11912398 | 0.94 | ALDH1A1 (0.33) | ALDH1A1TBXA2RCYP26B1PKMFOLH1 | |
| SCHEMBL3239947 | 0.93 | ALDH1A1 (0.32) | ALDH1A1CYP26B1 | |
| SCHEMBL15246873 | 0.91 | ADRB2 (0.30) | ADRB2HTR1AFOLH1 | |
| SCHEMBL9961373 | 0.91 | PKM (0.33) | CYP26B1PKMMAPK1 | |
| SCHEMBL15227488 | 0.90 | ADRB2 (0.32) | ALDH1A1TBXA2RCYP26B1PKMADRB2 | |
| SCHEMBL1715480 | 0.90 | ADRB2 (0.32) | ALDH1A1TBXA2RCYP26B1PKMADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11624089-B2 | Cyanine dyes | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2023-04-11 | — | — | US | disclosed |
| US-11053222-B2 | Fluorescent compounds | PIERCE BIOTECHNOLOGY, INC. (US) | 2021-07-06 | — | — | US | disclosed |
| US-20200232023-A1 | CYANINE DYES | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | 2020-07-23 | — | — | US | disclosed |
| US-10696653-B2 | Cyanine compounds | PIERCE BIOTECHNOLOGY, INC. (US) | 2020-06-30 | — | — | US | disclosed |
| US-10392659-B2 | Cyanine dyes | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2019-08-27 | — | — | US | disclosed |
| US-10351551-B2 | Fluorescent compounds | PIERCE BIOTECHNOLOGY, INC. (US) | 2019-07-16 | — | — | US | disclosed |
| EP-3081564-B1 | INDOLE DERIVATIVES AS LABELING DYE FOR BIOMOLECULE | PIERCE BIOTECHNOLOGY INC (US) | 2019-07-10 | — | — | EP | disclosed |
| US-20180327387-A1 | Cyanine Compounds | PIERCE BIOTECHNOLOGY, INC. (US) | 2018-11-15 | — | — | US | disclosed |
| US-10053447-B2 | Fluorescent compounds | PIERCE BIOTECHNOLOGY, INC (US) | 2018-08-21 | — | — | US | disclosed |
| EP-3029027-B1 | FLUORESCENT COMPOUNDS | PIERCE BIOTECHNOLOGY INC (US) | 2018-06-27 | — | — | EP | disclosed |
| EP-2655327-A1 | FLUORESCENT COMPOUNDS | Pierce Biotechnology, Inc. (US) | 2013-10-30 | — | — | EP | disclosed |
| US-20130251637-A9 | FLUORESCENT COMPOUNDS | DYOMICS GMBH (DE) | 2013-09-26 | — | — | US | disclosed |
| WO-2013130761-A1 | INDOLE DERIVATIVES AS LABELING DYE FOR BIOMOLECULE | PIERCE BIOTECHNOLOGY, INC. (US) | 2013-09-06 | — | — | WO | disclosed |
| US-20130230466-A1 | CYANINE COMPOUNDS | HERMANSON GREG (US) | 2013-09-05 | — | — | US | disclosed |
| US-20120294807-A9 | FLUORESCENT COMPOUNDS | DYOMICS GMBH (DE) | 2012-11-22 | — | — | US | disclosed |
| WO-2012088007-A1 | FLUORESCENT COMPOUNDS | PIERCE BIOTECHNOLOGY, INC. (US) | 2012-06-28 | — | — | WO | disclosed |
| US-20120156140-A1 | FLUORESCENT COMPOUNDS | DYOMICS GMBH (DE) | 2012-06-21 | — | — | US | disclosed |
| US-20120058469-A1 | FUNCTIONALIZED CYANINE DYES (PEG) | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2012-03-08 | — | — | US | disclosed |
| US-20120058482-A1 | FUNCTIONALIZED CYANINE DYES (PEG) | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2012-03-08 | — | — | US | disclosed |
| US-20120052506-A1 | CYANINE DYES | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2012-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (14 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10392659-B2 | Cyanine dyes | ABCG2, IK, ACR | ALDH1A1 1447/4885TBXA2R 4739/4885CYP26B1 2082/4885 |
| US-10351551-B2 | Fluorescent compounds | NCL, FUS, EFTUD2 | ALDH1A1 2481/4885TBXA2R 3775/4885CYP26B1 4096/4885 |
| US-11624089-B2 | Cyanine dyes | ABCG2, IK, ACR | ALDH1A1 1447/4885TBXA2R 4739/4885CYP26B1 2082/4885 |
| US-20180327387-A1 | Cyanine Compounds | NCL, NOP58, NAT10 | ALDH1A1 3956/4885TBXA2R 4841/4885CYP26B1 4610/4885 |
| US-20120156140-A1 | FLUORESCENT COMPOUNDS | NCL, FUS, EFTUD2 | ALDH1A1 2481/4885TBXA2R 3775/4885CYP26B1 4096/4885 |
| US-10696653-B2 | Cyanine compounds | NCL, NOP58, NAT10 | ALDH1A1 3956/4885TBXA2R 4841/4885CYP26B1 4610/4885 |
| US-20130230466-A1 | CYANINE COMPOUNDS | NCL, NOP58, NAT10 | ALDH1A1 3956/4885TBXA2R 4841/4885CYP26B1 4610/4885 |
| US-20120052506-A1 | CYANINE DYES | ABCG2, IK, ACR | ALDH1A1 1447/4885TBXA2R 4739/4885CYP26B1 2082/4885 |
| US-20200232023-A1 | CYANINE DYES | ABCG2, IK, ACR | ALDH1A1 1447/4885TBXA2R 4739/4885CYP26B1 2082/4885 |
| US-11053222-B2 | Fluorescent compounds | NCL, FUS, EFTUD2 | ALDH1A1 2481/4885TBXA2R 3775/4885CYP26B1 4096/4885 |
| US-20120058482-A1 | FUNCTIONALIZED CYANINE DYES (PEG) | ACR, IK, EGFR | ALDH1A1 1508/4885TBXA2R 4718/4885CYP26B1 2387/4885 |
| US-20130251637-A9 | FLUORESCENT COMPOUNDS | NCL, FUS, EFTUD2 | ALDH1A1 2481/4885TBXA2R 3775/4885CYP26B1 4096/4885 |
| US-10053447-B2 | Fluorescent compounds | NCL, FUS, EFTUD2 | ALDH1A1 2481/4885TBXA2R 3775/4885CYP26B1 4096/4885 |
| US-20120294807-A9 | FLUORESCENT COMPOUNDS | NCL, FUS, EFTUD2 | ALDH1A1 2481/4885TBXA2R 3775/4885CYP26B1 4096/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.