SCHEMBL17826331

SCHEMBL17826331

CC(C)=CCC1C(O)C=CC(=O)C1C

nearest known ligand 0.35

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.35
ABCB11 O95342 1/20 0.35
PTGS1 P23219 1/20 0.35
ALDH1A1 P00352 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2C9 P11712 1/20 0.32
ALOX15 P16050 1/20 0.32
ALOX12 P18054 1/20 0.32
CYP2C19 P33261 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HIF1A Q16665 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18022189 1.00 LMNA (0.35) LMNAABCB11PTGS1ALDH1A1CYP1A2
SCHEMBL18023679 1.00 LMNA (0.35) LMNAABCB11PTGS1ALDH1A1CYP1A2
SCHEMBL18022151 0.85 CYP3A4 (0.51) LMNAPTGS1ALDH1A1CYP1A2CYP3A4
SCHEMBL18022139 0.85 CYP3A4 (0.51) LMNAPTGS1ALDH1A1CYP1A2CYP3A4
SCHEMBL17441601 0.82
SCHEMBL17826336 0.80 MAPT (0.33) LMNAABCB11PTGS1CYP3A4CYP2C19
SCHEMBL18022145 0.80 ALDH1A1 (0.43) LMNAPTGS1ALDH1A1CYP1A2CYP3A4
SCHEMBL18022156 0.78 LMNA (0.42) LMNAALDH1A1CYP1A2CYP3A4CYP2C9
SCHEMBL18034094 0.78 LMNA (0.42) LMNAALDH1A1CYP1A2CYP3A4CYP2C9
SCHEMBL13757620 0.76 LMNA (0.38) LMNAABCB11PTGS1ALDH1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2958883-B1 CYCLOHEXENONE COMPOSITIONS AND PROCESS FOR MAKING THEREOF GOLDEN BIOTECHNOLOGY CORP (US) 2019-01-30 EP disclosed
US-20160251308-A1 Cyclohexenone Compositions and Process for Making Thereof GOLDEN BIOTECHNOLOGY CORP (US) 2016-09-01 US disclosed
US-20160251308-A1 Cyclohexenone Compositions and Process for Making Thereof GOLDEN BIOTECHNOLOGY CORP (US) 2016-09-01 US disclosed
WO-2016133940-A1 ANTICANCER AGENTS AND PROCESS OF MAKING THEREOF GOLDEN BIOTECHNOLOGY CORPORATION (US) 2016-08-25 WO disclosed
US-20160237012-A1 ANTICANCER AGENTS AND PROCESS OF MAKING THEREOF GOLDEN BIOTECHNOLOGY CORPORATION 2016-08-18 US disclosed
US-20160237012-A1 ANTICANCER AGENTS AND PROCESS OF MAKING THEREOF GOLDEN BIOTECHNOLOGY CORPORATION 2016-08-18 US disclosed
US-9365481-B2 Cyclohexenone compositions and process for making thereof GOLDEN BIOTECHNOLOGY CORPORATION (US) 2016-06-14 US disclosed
US-9365481-B2 Cyclohexenone compositions and process for making thereof GOLDEN BIOTECHNOLOGY CORPORATION (US) 2016-06-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160237012-A1 ANTICANCER AGENTS AND PROCESS OF MAKING THEREOF MCL1, HCCS, CASP3 LMNA 1228/4885ABCB11 2453/4885PTGS1 2173/4885
US-20160251308-A1 Cyclohexenone Compositions and Process for Making Thereof HSD17B7, CYP17A1, CYP51A1 LMNA 379/4885ABCB11 3131/4885PTGS1 801/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.