Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1D1 | P20393 | 1/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | UBE2M | P61081 | 5/20 | 0.38 |
| ▸ | DCUN1D1 | Q96GG9 | 5/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | VNN1 | O95497 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | PTGES | O14684 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17826743 | 0.90 | NR1D1 (0.41) | NR1D1NR1H3PKMUBE2MDCUN1D1 | |
| SCHEMBL1114708 | 0.75 | NR1D1 (0.42) | NR1D1NR1H3PKMUBE2MDCUN1D1 | |
| SCHEMBL3242548 | 0.75 | SMN1; SMN2 (0.49) | NR1D1NR1H3NAMPTVNN1GPBAR1 | |
| SCHEMBL2396944 | 0.70 | GRIN2B (0.40) | NR1D1NR1H3PKMUBE2MDCUN1D1 | |
| SCHEMBL1114600 | 0.66 | CASP3 (0.44) | — | |
| SCHEMBL1114301 | 0.65 | SMN1; SMN2 (0.49) | NR1D1NR1H3NAMPTVNN1GPBAR1 | |
| SCHEMBL8390987 | 0.64 | HDAC1 (0.43) | KMT2A | |
| SCHEMBL1114279 | 0.63 | MAPT (0.43) | LMNAPOLB | |
| SCHEMBL28977515 | 0.63 | VNN1 (0.54) | NR1D1NR1H3NAMPTMEN1KMT2A | |
| SCHEMBL3235226 | 0.63 | SCD5 (0.57) | MEN1KMT2ALMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2278879-B1 | COMPOUNDS, COMPOSITIONS AND METHODS COMPRISING OXADIAZOLE DERIVATIVES | PATH DRUG SOLUTIONS (US) | 2016-06-15 | — | — | EP | disclosed |