Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1784408 | 0.88 | ELANE (0.44) | ELANENPC1RAB9AMEN1HPGD | |
| SCHEMBL944302 | 0.81 | TSHR (0.43) | NPC1RAB9AMEN1HPGDKMT2A | |
| SCHEMBL277747 | 0.81 | ELANE (0.52) | ELANENPC1RAB9AMEN1HPGD | |
| SCHEMBL14816308 | 0.78 | MAOA (0.49) | ELANENPC1RAB9AHPGDCYP2A6 | |
| SCHEMBL575883 | 0.78 | HDAC7 (0.46) | ELANENPC1RAB9AMEN1HPGD | |
| SCHEMBL29590360 | 0.76 | ELANE (0.52) | ELANENPC1RAB9AMEN1HPGD | |
| SCHEMBL11729295 | 0.76 | ELANE (0.52) | ELANENPC1RAB9AMEN1HPGD | |
| SCHEMBL16768825 | 0.75 | HTR1A (0.45) | NPC1RAB9AMAPTTP53CYP2A6 | |
| SCHEMBL15430420 | 0.73 | HPGD (0.59) | ELANENPC1RAB9AMEN1HPGD | |
| SCHEMBL31746199 | 0.73 | HPGD (0.59) | ELANENPC1RAB9AMEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2323975-B1 | MULTI-RING ANTIOXIDANTS WITH ANTIWEAR PROPERTIES | SI GROUP INC (US) | 2019-04-24 | — | — | EP | disclosed |
| US-20110124540-A1 | MULTI-RING ANTIOXIDANTS WITH ANTIWEAR PROPERTIES | ALBEMARLE CORPORATION (US) | 2011-05-26 | — | — | US | disclosed |
| EP-2323975-A2 | MULTI-RING ANTIOXIDANTS WITH ANTIWEAR PROPERTIES | Albemarle Corporation (US) | 2011-05-25 | — | — | EP | disclosed |
| WO-2010011523-A2 | MULTI-RING ANTIOXIDANTS WITH ANTIWEAR PROPERTIES | ALBEMARLE CORPORATION (US) | 2010-01-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110124540-A1 | MULTI-RING ANTIOXIDANTS WITH ANTIWEAR PROPERTIES | GSR, CBR1, SOD1 | ELANE 2215/4885NPC1 2328/4885RAB9A 1806/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.