Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | METAP2 | P50579 | 1/20 | 0.43 |
| ▸ | IDH1 | O75874 | 7/20 | 0.41 |
| ▸ | IDH2 | P48735 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.40 |
| ▸ | BRD7 | Q9NPI1 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.37 |
| ▸ | PHGDH | O43175 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ERN1 | O75460 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9007764 | 0.87 | BRD9 (0.41) | CYP1A2METAP2BRD9BRD7POLB | |
| SCHEMBL18287252 | 0.81 | CYP1A2 (0.44) | GABRA1GABRG2GABRB3GABRA3CYP1A2 | |
| SCHEMBL17826973 | 0.78 | CCR1 (0.48) | CYP1A2METAP2BRD9BRD7POLB | |
| SCHEMBL29688303 | 0.77 | GABRA1 (0.51) | GABRA1GABRG2GABRB3GABRA3IDH1 | |
| SCHEMBL11999816 | 0.77 | GABRA1 (0.51) | GABRA1GABRG2GABRB3GABRA3IDH1 | |
| SCHEMBL31438401 | 0.73 | BRD9 (0.56) | CYP1A2METAP2BRD9BRD7POLB | |
| SCHEMBL17276010 | 0.73 | BRD9 (0.56) | CYP1A2METAP2BRD9BRD7POLB | |
| SCHEMBL18287242 | 0.72 | TDP1 (0.45) | BRD9BRD7POLBTDP1TGFBR1 | |
| SCHEMBL8514010 | 0.72 | SMN1; SMN2 (0.50) | CYP1A2GAABRD9BRD7POLB | |
| SCHEMBL2083715 | 0.71 | CYP1A2 (0.52) | CYP1A2METAP2BRD9BRD7POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200283403-A1 | NOVEL COMPOUNDS AND COMPOSITIONS FOR THE INHIBITION OF NAMPT | Valo Health, LLC | 2020-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200283403-A1 | NOVEL COMPOUNDS AND COMPOSITIONS FOR THE INHIBITION OF NAMPT | NAMPT, HAMP, NQO1 | GABRA1 3660/4885GABRG2 4156/4885GABRB3 3222/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.