Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 2/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.38 |
| ▸ | CBFB | Q13951 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 5/20 | 0.35 |
| ▸ | RAB9A | P51151 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TNKS | O95271 | 1/20 | 0.35 |
| ▸ | SCD | O00767 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1581469 | 0.80 | PDE10A (0.43) | PDE10ANPC1RAB9AMAPTKDM4E | |
| SCHEMBL30335253 | 0.80 | CA12 (0.50) | CASP3SENP7SENP8SENP6CBFB | |
| SCHEMBL3147993 | 0.80 | CA12 (0.50) | CASP3SENP7SENP8SENP6CBFB | |
| SCHEMBL17826982 | 0.79 | MAPT (0.56) | CASP3SENP7SENP8SENP6NPC1 | |
| SCHEMBL2614947 | 0.77 | PDE10A (0.45) | NAAACASP3SENP7SENP8SENP6 | |
| SCHEMBL2609406 | 0.73 | TNKS (0.37) | NAAACASP3SENP7SENP8SENP6 | |
| SCHEMBL2440495 | 0.71 | GRM5 (0.38) | NAAACASP3SENP7SENP8SENP6 | |
| SCHEMBL16656143 | 0.71 | CCR1 (0.67) | CASP3SENP7GRM5RXFP1NPC1 | |
| SCHEMBL9082334 | 0.70 | ALDH1A1 (0.47) | CASP3SENP7SENP8SENP6NPC1 | |
| SCHEMBL18851549 | 0.69 | MCHR1 (0.43) | CASP3SENP7SENP8SENP6PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2379535-B1 | 7-PHENOXYCHROMAN CARBOXYLIC ACID DERIVATIVES | ARRAY BIOPHARMA INC (US) | 2016-06-15 | — | — | EP | disclosed |