Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.67 |
| ▸ | CCR5 | P51681 | 1/20 | 0.67 |
| ▸ | CCR8 | P51685 | 1/20 | 0.67 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.67 |
| ▸ | METAP2 | P50579 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | TNKS | O95271 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 6/20 | 0.41 |
| ▸ | RAB9A | P51151 | 6/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.40 |
| ▸ | NOS2 | P35228 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30335253 | 0.89 | CA12 (0.50) | CCR1CCR5CCR8HDAC6ACHE | |
| SCHEMBL3147993 | 0.89 | CA12 (0.50) | CCR1CCR5CCR8HDAC6ACHE | |
| SCHEMBL17754087 | 0.84 | RXFP1 (0.54) | CCR1CCR5CCR8HDAC6METAP2 | |
| SCHEMBL765406 | 0.84 | RXFP1 (0.58) | CCR1CCR5CCR8HDAC6ACHE | |
| SCHEMBL9968574 | 0.82 | KDM1A (0.46) | CCR1CCR5CCR8HDAC6METAP2 | |
| Abametapir SCHEMBL29374261 | 0.82 | CCR1 (1.00) | CCR1CCR5CCR8HDAC6METAP2 | |
| Abametapir SCHEMBL351152 | 0.82 | CCR1 (1.00) | CCR1CCR5CCR8HDAC6METAP2 | |
| SCHEMBL14777077 | 0.81 | RELA (0.62) | CCR1CCR5CCR8HDAC6CYP3A4 | |
| SCHEMBL14777075 | 0.81 | RELA (0.62) | CCR1CCR5CCR8HDAC6CYP3A4 | |
| SCHEMBL2614947 | 0.79 | PDE10A (0.45) | CCR1CCR5CCR8HDAC6TNKS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9406943-B2 | Electrocatalysts using porous polymers and method of preparation | UCHICAGO ARGONNE, LLC (US) | 2016-08-02 | — | — | US | disclosed |
| US-20150194681-A1 | ELECTROCATALYSTS USING POROUS POLYMERS AND METHOD OF PREPARATION | UCHICAGO ARGONNE, LLC (US) | 2015-07-09 | — | — | US | disclosed |
| US-9012344-B2 | Electrocatalysts using porous polymers and method of preparation | UCHICAGO ARGONNE, LLC (US) | 2015-04-21 | — | — | US | disclosed |