SCHEMBL3147993

SCHEMBL3147993

COc1ccc(-c2ccc(OC)cn2)nc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
CA7 P43166 1/20 0.50
CA9 Q16790 1/20 0.50
CA14 Q9ULX7 1/20 0.50
RXFP1 Q9HBX9 1/20 0.47
NPC1 O15118 5/20 0.47
RAB9A P51151 5/20 0.47
CASP3 P42574 2/20 0.47
SENP7 Q9BQF6 2/20 0.47
CCR1 P32246 2/20 0.46
CCR5 P51681 2/20 0.46
CCR8 P51685 2/20 0.46
HDAC6 Q9UBN7 1/20 0.46
TNKS O95271 1/20 0.44
SENP8 Q96LD8 1/20 0.43
SENP6 Q9GZR1 1/20 0.43
CBFB Q13951 1/20 0.43
MAPT P10636 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30335253 1.00 CA12 (0.50) CA12CA1CA2CA7CA9
SCHEMBL16656143 0.89 CCR1 (0.67) CA12CA1CA2CA7CA9
SCHEMBL25195228 0.85 LMNA (0.54) NPC1RAB9ACCR1CCR5CCR8
SCHEMBL29419008 0.85 LMNA (0.54) NPC1RAB9ACCR1CCR5CCR8
SCHEMBL2467429 0.84 CLK4 (0.59) RXFP1NPC1RAB9ACCR1CCR5
SCHEMBL2614947 0.84 PDE10A (0.45) CA12CA1CA2CA7CA9
SCHEMBL20086110 0.84 HAO1 (0.43) CA12CA1CA2CA7CA9
SCHEMBL13341651 0.83 NPC1 (0.62) RXFP1NPC1RAB9ACASP3SENP7
SCHEMBL20086109 0.82 CYP19A1 (0.45) RXFP1NPC1RAB9ACASP3SENP7
SCHEMBL15258007 0.82 ALDH1A1 (0.57) RXFP1NPC1RAB9ATNKSMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4727953-A2 ACCELERATED MARKING OF 5-FORMYL CYTOSINE AND USE IN NUCLEIC ACID METHYLATION SEQUENCING F. Hoffmann-La Roche AG (CH) 2026-04-22 EP claimed
WO-2024256358-A2 ACCELERATED MARKING OF 5-FORMYL CYTOSINE AND USE IN NUCLEIC ACID METHYLATION SEQUENCING F. HOFFMANN-LA ROCHE AG (CH) 2024-12-19 WO claimed
US-20230167144-A1 PREPARATION AND ITS APPLICATION OF A CYANIDE-BRIDGED METAL ORGANIC COMPOUND WITH INTRAMOLECULAR MAGNETIC TRANSFORMATION Hubei Jingmen Industrial Technology Research Institute Co., Ltd. (CN) 2023-06-01 US claimed
CN-115094463-A Sub-nanometer alloy material and preparation method and application thereof 中国科学院上海高等研究院 2022-09-23 CN claimed
CN-110628038-A Covalent triazine organic framework, limited-area metal catalyst, preparation method and application 中国科学院上海高等研究院 2019-12-31 CN claimed
EP-4735170-A1 METATHESIS COMPOSITIONS COMPRISING AIR-STABLE IMIDO ALKYLIDENE COMPLEXES Verbio SE (DE) 2026-05-06 EP disclosed
EP-4727953-A2 ACCELERATED MARKING OF 5-FORMYL CYTOSINE AND USE IN NUCLEIC ACID METHYLATION SEQUENCING F. Hoffmann-La Roche AG (CH) 2026-04-22 EP disclosed
WO-2025003441-A1 METATHESIS COMPOSITIONS COMPRISING AIR-STABLE IMIDO ALKYLIDENE COMPLEXES VERBIO VEREINIGTE BIOENERGIE AG (DE) 2025-01-02 WO disclosed
WO-2024256358-A2 ACCELERATED MARKING OF 5-FORMYL CYTOSINE AND USE IN NUCLEIC ACID METHYLATION SEQUENCING F. HOFFMANN-LA ROCHE AG (CH) 2024-12-19 WO disclosed
US-11890604-B2 Composite catalyst for carbon dioxide reduction and method of fabricating of the same KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION, SEJONG CAMPUS (KR) 2024-02-06 US disclosed
US-11773074-B2 Method for aerobic oxidative coupling of thiophenes with a ligand-supported palladium catalyst WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2023-10-03 US disclosed
US-11773074-B2 Method for aerobic oxidative coupling of thiophenes with a ligand-supported palladium catalyst WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2023-10-03 US disclosed
US-8455690-B2 Method for producing arylhydroxylamine WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2013-06-04 US disclosed
US-8182695-B2 Bridged macrocyclic module compositions WHITEFORD JEFFERY A (US) 2012-05-22 US disclosed
US-7872059-B2 Polyurethanes, acryl resins, and metal (cobalt, nickel, palladium, and/or ruthenium); engravable flexographic printing plate precursor FUJIFILM CORPORATION (JP) 2011-01-18 US disclosed
US-20100113830-A1 METHOD FOR PRODUCING ARYLHYDROXYLAMINE WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2010-05-06 US disclosed
EP-2154125-A1 METHOD FOR PRODUCING ARYLHYDROXYLAMINE Wako Pure Chemical Industries, Ltd. (JP) 2010-02-17 EP disclosed
US-20080290034-A1 Bridged macrocyclic module compositions COVALENT PARTNERS LLC 2008-11-27 US disclosed
US-20080194762-A1 Polyurethanes, acryl resins, and metal (cobalt, nickel, palladium, and/or ruthenium); engravable flexographic printing plate precursor FUJIFILM CORPORATION (JP) 2008-08-14 US disclosed
US-7368564-B2 Bridged macrocyclic module compositions COVALENT PARTNERS, LLC (US) 2008-05-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100113830-A1 METHOD FOR PRODUCING ARYLHYDROXYLAMINE PAH, APEH, HPD CA12 653/4885CA1 129/4885CA2 442/4885
US-11773074-B2 Method for aerobic oxidative coupling of thiophenes with a ligand-supported palladium catalyst PPOX, TST, COX6C CA12 3670/4885CA1 3405/4885CA2 2851/4885
US-20080290034-A1 Bridged macrocyclic module compositions SBDS, NCL, INTS6 CA12 3362/4885CA1 3401/4885CA2 4609/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.