Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.56 |
| ▸ | NPC1 | O15118 | 6/20 | 0.56 |
| ▸ | RAB9A | P51151 | 6/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.56 |
| ▸ | PKM | P14618 | 3/20 | 0.56 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.48 |
| ▸ | HTR2A | P28223 | 3/20 | 0.48 |
| ▸ | HRH2 | P25021 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24046966 | 0.79 | SMN1; SMN2 (0.56) | MAPTNPC1RAB9ASMN1; SMN2PKM | |
| SCHEMBL17826975 | 0.79 | NAAA (0.39) | MAPTNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL4592220 | 0.79 | MCHR1 (0.55) | MAPTNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL17826979 | 0.78 | SMN1; SMN2 (0.43) | MAPTNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL17826983 | 0.78 | NPC1 (0.47) | MAPTNPC1RAB9ASMN1; SMN2PKM | |
| SCHEMBL17184615 | 0.78 | KEAP1 (0.40) | MAPTNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL17184668 | 0.78 | NPC1 (0.39) | MAPTNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL4591645 | 0.78 | MCHR1 (0.48) | MAPTNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL9629460 | 0.77 | MAPT (0.59) | MAPTNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL25591566 | 0.77 | MAPT (0.62) | MAPTNPC1RAB9ASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2379535-B1 | 7-PHENOXYCHROMAN CARBOXYLIC ACID DERIVATIVES | ARRAY BIOPHARMA INC (US) | 2016-06-15 | — | — | EP | disclosed |