SCHEMBL17827124

SCHEMBL17827124

O=NC(C1CC1)N1CCCCC1

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
FDPS P14324 2/20 0.33
DPP4 P27487 2/20 0.32
DPP7 Q9UHL4 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5843787 0.65 FDPS (0.31) FDPS
SCHEMBL20633452 0.65 FDPS (0.36) FDPS
SCHEMBL7117094 0.62 DPP7 (0.34) DPP4DPP7
SCHEMBL382220 0.60
SCHEMBL14210627 0.59 FDPS (0.39) FDPS
SCHEMBL4243171 0.58 EPHX1 (0.39)
SCHEMBL9416347 0.58 EPHX1 (0.39)
SCHEMBL1414278 0.57 FDPS (0.41) FDPSDPP7
SCHEMBL194338 0.56
SCHEMBL10944140 0.55 OPRM1 (0.40) FDPS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3031324-A2 TRICYCLIC KINASE INHIBITORS AbbVie Inc. (US) 2016-06-15 EP disclosed