Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | RGS12 | O14924 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12623251 | 0.76 | ACHE (0.52) | ALDH1A1ALOX15MAPK1TDP1CYP3A4 | |
| SCHEMBL11224665 | 0.74 | ALDH1A1 (0.41) | ALDH1A1ALOX15MAPK1TDP1TP53 | |
| SCHEMBL62465 | 0.73 | ALOX15 (0.50) | ALDH1A1ALOX15MAPK1TDP1TP53 | |
| Hydrochloric Acid SCHEMBL11091263 | 0.72 | ALOX15 (0.48) | ALDH1A1ALOX15MAPK1TDP1TP53 | |
| SCHEMBL11325204 | 0.71 | ALDH1A1 (0.52) | ALDH1A1ALOX15MAPK1TDP1TP53 | |
| SCHEMBL9638465 | 0.70 | ALDH1A1 (0.52) | ALDH1A1ALOX15MAPK1TDP1TP53 | |
| SCHEMBL1760716 | 0.69 | TSHR (0.57) | ALDH1A1ALOX15MAPK1TDP1TP53 | |
| SCHEMBL15449411 | 0.69 | SELL (0.58) | ALDH1A1ALOX15TDP1TP53CYP3A4 | |
| SCHEMBL17265773 | 0.69 | ALDH1A1 (0.52) | ALDH1A1ALOX15MAPK1TDP1TP53 | |
| SCHEMBL10666795 | 0.69 | ALDH1A1 (0.56) | ALDH1A1ALOX15TP53TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3031797-A1 | Hydrodabcyl | Universität Bayreuth (DE) | 2016-06-15 | — | — | EP | disclosed |