SCHEMBL62465

SCHEMBL62465

CN(C)c1ccc(N)c(O)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 4/20 0.50
HSD17B10 Q99714 4/20 0.50
CYP3A4 P08684 2/20 0.50
ALDH1A1 P00352 5/20 0.46
MAPK1 P28482 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
TP53 P04637 1/20 0.46
KDM4E B2RXH2 3/20 0.45
TSHR P16473 2/20 0.45
MAPT P10636 2/20 0.45
MEN1 O00255 2/20 0.45
POLB P06746 2/20 0.45
KMT2A Q03164 2/20 0.45
GAA P10253 1/20 0.45
RAB9A P51151 1/20 0.45
APAF1 O14727 1/20 0.42
MAOA P21397 1/20 0.41
MAOB P27338 1/20 0.41
APP P05067 2/20 0.40
TERT O14746 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11091263 0.98 ALOX15 (0.48) ALOX15HSD17B10CYP3A4ALDH1A1MAPK1
SCHEMBL13922319 0.82 ALDH1A1 (0.52) ALOX15HSD17B10CYP3A4ALDH1A1MAPK1
SCHEMBL25540950 0.78 ALDH1A1 (0.59) ALOX15HSD17B10ALDH1A1MAPK1TDP1
SCHEMBL2313495 0.78 ALDH1A1 (0.52) ALOX15HSD17B10CYP3A4ALDH1A1MAPK1
SCHEMBL31361979 0.78 ALDH1A1 (0.52) ALOX15HSD17B10CYP3A4ALDH1A1MAPK1
SCHEMBL5929100 0.77 ALOX15 (0.45) ALOX15HSD17B10CYP3A4ALDH1A1MAPK1
SCHEMBL11011080 0.77 S100B (0.63) ALOX15HSD17B10CYP3A4ALDH1A1MAPK1
SCHEMBL29740082 0.77 S100B (0.63) ALOX15HSD17B10CYP3A4ALDH1A1MAPK1
SCHEMBL24849436 0.77 ALOX15 (0.41) ALOX15HSD17B10CYP3A4ALDH1A1MAPK1
SCHEMBL10941939 0.77 HSD17B10 (0.41) ALOX15HSD17B10CYP3A4ALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-3062857-A None JP disclosed
WO-2021257966-A1 ERG ONCOGENE INHIBITORS THE HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC. (US) 2021-12-23 WO disclosed
EP-3313363-A1 PROTECTIVE AND RESTRUCTURING HAIR COMPOSITION H.S.A. Hair Styling Applications S.P.A. (IT) 2018-05-02 EP disclosed
WO-2016207840-A1 PROTECTIVE AND RESTRUCTURING HAIR COMPOSITION REEF COSMETICS SA (CH) 2016-12-29 WO disclosed
US-8129525-B2 Long wavelength thiol-reactive fluorophores BECTON DICKINSON AND COMPANY (US) 2012-03-06 US disclosed
US-8129525-B2 Long wavelength thiol-reactive fluorophores BECTON DICKINSON AND COMPANY (US) 2012-03-06 US disclosed
US-8071794-B2 Long wavelength thiol-reactive fluorophores BECTON, DICKINSON AND COMPANY (US) 2011-12-06 US disclosed
US-8071794-B2 Long wavelength thiol-reactive fluorophores BECTON, DICKINSON AND COMPANY (US) 2011-12-06 US disclosed
US-20110184168-A1 LONG WAVELENGTH THIOL-REACTIVE FLUOROPHORES BECTON, DICKINSON AND COMPANY (US) 2011-07-28 US disclosed
US-20110184168-A1 LONG WAVELENGTH THIOL-REACTIVE FLUOROPHORES BECTON, DICKINSON AND COMPANY (US) 2011-07-28 US disclosed
EP-0253534-A2 Silver halide photographic paper improved in remaining curl KONICA CORPORATION (JP) 1988-01-20 EP disclosed
EP-0253585-A2 Silver halide light-sensitive photographic material KONICA CORPORATION (JP) 1988-01-20 EP disclosed
EP-0181728-A2 Light-sensitive silver halide photographic material KONICA CORPORATION (JP) 1986-05-21 EP disclosed
CN-85108256-A LIGHT-SENSITIVE SILVER HALIDE PHOTOGRAPHIC MATERIAL 1986-05-10 CN disclosed
US-4581327-A CORE AND SHELL STRUCTURES, RHODIUM DOPED SHELLS, HARDNESS OF TONE, STORAGE STABILITY KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1986-04-08 US disclosed
EP-0146302-A1 Light-sensitive silver halide photographic material for direct-post and method for processing the same KONICA CORPORATION (JP) 1985-06-26 EP disclosed
US-4444875-A LAYER OF A TETRAZOLIUM COMPOUND KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1984-04-24 US disclosed
US-4329417-A OXIDIZERS AND QUATERNARY AMMONIUM SALTS, PHOSPHONIUM SALTS OR SULFONIUM SALTS KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1982-05-11 US disclosed
US-4211835-A TETRAZOLIUM COMPOUND, BLACK AND WHITE, HIGH CONTRAST KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1980-07-08 US disclosed
US-4192682-A NON-DIFFUSIBLE COMPOUND HAVING OXIDATION POWER ON A HYDROQUINONE DEVELOPING AGENT; DEVELOPER CONTAINING NO HYDROQUINONE KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1980-03-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110184168-A1 LONG WAVELENGTH THIOL-REACTIVE FLUOROPHORES NUCB2, NDC1, NCBP1 ALOX15 3704/4885HSD17B10 1607/4885CYP3A4 1548/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.