Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 15/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.35 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 4/20 | 0.34 |
| ▸ | MMP3 | P08254 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17827831 | 0.90 | CA12 (0.37) | RORCSIRT2SIRT1 | |
| SCHEMBL17827833 | 0.87 | SIRT2 (0.40) | RORCSIRT2SIRT1 | |
| SCHEMBL17819968 | 0.87 | CXCR2 (0.33) | — | |
| SCHEMBL17827850 | 0.82 | RORC (0.41) | RORCMMP8MMP3 | |
| SCHEMBL17827863 | 0.81 | SIRT2 (0.40) | RORCSIRT2SIRT1 | |
| SCHEMBL17827851 | 0.80 | SIRT2 (0.38) | RORCSIRT2SIRT1 | |
| SCHEMBL17820990 | 0.77 | RAB9A (0.32) | — | |
| SCHEMBL16042474 | 0.76 | CA12 (0.43) | RORCSIRT2SIRT1 | |
| SCHEMBL13035973 | 0.76 | CA12 (0.43) | RORCSIRT2SIRT1 | |
| SCHEMBL17827847 | 0.74 | RORC (0.40) | RORCMMP8MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9586951-B2 | Morpholine derivative or salt thereof | FUJIFILM CORPORATION (JP) | 2017-03-07 | — | — | US | disclosed |
| US-9586951-B2 | Morpholine derivative or salt thereof | FUJIFILM CORPORATION (JP) | 2017-03-07 | — | — | US | disclosed |
| US-20160168139-A1 | NOVEL MORPHOLINE DERIVATIVE OR SALT THEREOF | FUJIFILM CORPORATION (JP) | 2016-06-16 | — | — | US | disclosed |
| US-20160168139-A1 | NOVEL MORPHOLINE DERIVATIVE OR SALT THEREOF | FUJIFILM CORPORATION (JP) | 2016-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160168139-A1 | NOVEL MORPHOLINE DERIVATIVE OR SALT THEREOF | PRMT7, RBBP7, RER1 | RORC 897/4885SIRT2 1326/4885SIRT1 1475/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.