SCHEMBL1782795

SCHEMBL1782795

CCCCCC(C)C(OC)C(C)=O

nearest known ligand 0.44

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
FAAH O00519 1/20 0.44
CA1 P00915 2/20 0.42
ZDHHC7 Q9NXF8 1/20 0.42
ABCB1 P08183 1/20 0.40
SMPD1 P17405 3/20 0.39
ACE2 Q9BYF1 1/20 0.39
GPR84 Q9NQS5 5/20 0.38
FFAR1 O14842 1/20 0.38
MAPT P10636 1/20 0.37
TP53 P04637 1/20 0.37
LCK P06239 1/20 0.37
PPARD Q03181 1/20 0.37
ZDHHC20 Q5W0Z9 1/20 0.37
ZDHHC2 Q9UIJ5 1/20 0.37
LMNA P02545 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1782165 0.94 CA2 (0.41) FAAHCA1ZDHHC7ABCB1LMNA
SCHEMBL1782784 0.86 METAP1 (0.36) FAAHCA1
SCHEMBL10596147 0.85 ACE2 (0.47) CA1ZDHHC7ABCB1ACE2GPR84
SCHEMBL28154034 0.81 CA1 (0.40) FAAHCA1ZDHHC7LMNA
SCHEMBL1784785 0.77 SLC1A3 (0.38) ACE2
SCHEMBL1782449 0.75 CA1 (0.48) FAAHCA1SMPD1ACE2GPR84
SCHEMBL1786112 0.74 METAP1 (0.34) FAAHCA1ZDHHC7ABCB1LMNA
SCHEMBL19001413 0.74 SPHK1 (0.48) FAAHCA1ACE2GPR84FFAR1
SCHEMBL27832077 0.74 FAAH (0.45) FAAHCA1ZDHHC7SMPD1ACE2
SCHEMBL1785198 0.74 ZDHHC7 (0.46) FAAHCA1ZDHHC7SMPD1GPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8632792-B2 Cooling sensation agent composition and sensory stimulation agent composition TAKASAGO INTERNATIONAL CORPORATION (JP) 2014-01-21 US disclosed
US-20110117147-A1 COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION TAKASAGO INTERNATIONAL CORPORATION (JP) 2011-05-19 US disclosed
WO-2009123355-A2 COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION TAKASAGO INTERNATIONAL CORPORATION (JP) 2009-10-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110117147-A1 COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION TRPA1, HRH1, HRH2 FAAH 94/4885CA1 3505/4885ZDHHC7 2528/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.