Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.71 |
| ▸ | ACHE | P22303 | 1/20 | 0.66 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.47 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17921687 | 0.86 | HRH3 (0.51) | HRH3ACHESIGMAR1HTR2AKCNH2 | |
| SCHEMBL12023880 | 0.84 | SIGMAR1 (0.75) | HRH3ACHESIGMAR1 | |
| SCHEMBL13001961 | 0.83 | HRH3 (0.75) | HRH3ACHESIGMAR1SPHK1 | |
| SCHEMBL23711032 | 0.81 | HRH3 (0.77) | HRH3ACHESIGMAR1SPHK1 | |
| SCHEMBL17828190 | 0.80 | HRH3 (0.75) | HRH3ACHESIGMAR1HTR2ASPHK1 | |
| SCHEMBL17828185 | 0.80 | HRH3 (0.75) | HRH3ACHESIGMAR1 | |
| SCHEMBL6419877 | 0.80 | HRH3 (0.75) | HRH3ACHESIGMAR1SPHK1 | |
| SCHEMBL14708456 | 0.80 | HRH3 (0.75) | HRH3ACHESIGMAR1HTR2AKCNH2 | |
| SCHEMBL152736 | 0.80 | ACHE (1.00) | HRH3ACHESIGMAR1HTR2AKCNH2 | |
| SCHEMBL23105175 | 0.77 | HRH3 (0.71) | HRH3ACHESIGMAR1SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9586951-B2 | Morpholine derivative or salt thereof | FUJIFILM CORPORATION (JP) | 2017-03-07 | — | — | US | disclosed |
| US-9586951-B2 | Morpholine derivative or salt thereof | FUJIFILM CORPORATION (JP) | 2017-03-07 | — | — | US | disclosed |
| US-20160168139-A1 | NOVEL MORPHOLINE DERIVATIVE OR SALT THEREOF | FUJIFILM CORPORATION (JP) | 2016-06-16 | — | — | US | disclosed |
| US-20160168139-A1 | NOVEL MORPHOLINE DERIVATIVE OR SALT THEREOF | FUJIFILM CORPORATION (JP) | 2016-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160168139-A1 | NOVEL MORPHOLINE DERIVATIVE OR SALT THEREOF | PRMT7, RBBP7, RER1 | HRH3 232/4885ACHE 1829/4885SIGMAR1 427/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.