SCHEMBL17828655

SCHEMBL17828655

CN(C(=O)CCl)C1CCN(C(=O)OC(C)(C)C)CC1

nearest known ligand 0.50

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.47
GPR119 Q8TDV5 10/20 0.46
USP30 Q70CQ3 2/20 0.46
RECQL P46063 1/20 0.45
EPHX1 P07099 1/20 0.45
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
USP2 O75604 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23144545 0.86 GPR119 (0.54) GPR119
SCHEMBL1089500 0.84 HPGD (0.46) HPGDGPR119USP30RECQLEPHX1
SCHEMBL16415863 0.84 EPHX1 (0.51) HPGDGPR119USP30RECQLEPHX1
SCHEMBL16409534 0.82 GPR119 (0.44) HPGDGPR119USP30RECQLEPHX1
SCHEMBL1827484 0.82 HPGD (0.51) HPGDGPR119USP30RECQLEPHX1
SCHEMBL27108296 0.82 GPR119 (0.47) HPGDGPR119USP30RECQLEPHX1
SCHEMBL7754719 0.81 USP30 (0.45) HPGDGPR119USP30RECQLEPHX1
SCHEMBL19026787 0.81 GPR119 (0.52) HPGDGPR119USP30RECQLEPHX1
SCHEMBL23144561 0.80 RECQL (0.52) GPR119RECQLUSP2SMN1; SMN2
SCHEMBL4711418 0.80 HPGD (0.55) HPGDGPR119USP30RECQLEPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111925367-B Fused ring derivative inhibitor, preparation method and application thereof 上海翰森生物医药科技有限公司 2023-07-07 CN disclosed
CN-111925367-A Fused ring derivative inhibitor, preparation method and application thereof 上海翰森生物医药科技有限公司 2020-11-13 CN disclosed
US-20160166560-A1 Urea Compounds and Their Use as FAAH Enzyme Inhibitors BIAL-PORTELA & CA, S.A. (PT) 2016-06-16 US disclosed
US-20160166560-A1 Urea Compounds and Their Use as FAAH Enzyme Inhibitors BIAL-PORTELA & CA, S.A. (PT) 2016-06-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160166560-A1 Urea Compounds and Their Use as FAAH Enzyme Inhibitors FAAH, FAAH2, HRH2 HPGD 491/4885GPR119 436/4885USP30 200/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.