Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.41 |
| ▸ | STS | P08842 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17828655 | 0.81 | HPGD (0.47) | USP30GPR119HPGDMEN1KMT2A | |
| SCHEMBL1089500 | 0.80 | HPGD (0.46) | USP30GPR119HPGDRECQLEPHX1 | |
| SCHEMBL16219487 | 0.80 | CCR5 (0.38) | — | |
| SCHEMBL544238 | 0.78 | FAAH (0.58) | GPR119HPGDRECQLEPHX1 | |
| SCHEMBL16409534 | 0.78 | GPR119 (0.44) | USP30GPR119HPGDMEN1KMT2A | |
| SCHEMBL1827484 | 0.78 | HPGD (0.51) | USP30GPR119HPGDMEN1KMT2A | |
| SCHEMBL14980461 | 0.78 | MCHR1 (0.46) | KMT2A | |
| SCHEMBL27108296 | 0.77 | GPR119 (0.47) | USP30GPR119HPGDMEN1KMT2A | |
| SCHEMBL28774247 | 0.77 | GPR119 (0.36) | GPR119HPGDMEN1KMT2ARECQL | |
| SCHEMBL16105020 | 0.77 | EPHX1 (0.49) | USP30GPR119HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0725059-B1 | 2,3-DIAMINOPROPIONIC ACID DERIVATIVE | SUMITOMO PHARMA (JP) | 2001-01-17 | — | — | EP | disclosed |
| US-6048854-A | ANTICOAGULANTS; ANTICANCER AGENT; WOUND HEALING AGENTS;BONE DISORDERS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2000-04-11 | — | — | US | disclosed |
| US-5707994-A | USEFUL AS A PLATELET AGGREGATION INHIBITOR, CANCER METASTASIS INHIBITOR, WOUND HEALING AGENT OR A BONE RESORPTION INHIBITOR | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-01-13 | — | — | US | disclosed |
| EP-0725059-A1 | 2,3-DIAMINOPROPIONIC ACID DERIVATIVE | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1996-08-07 | — | — | EP | disclosed |