SCHEMBL17829381

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17829362	0.98	TSHR (0.46)	MMP9KDM4ETP53MAPTTSHR
	SCHEMBL21131637	0.97	CKS1B (0.42)	MMP9KDM4ETP53MAPTTSHR
	SCHEMBL21131830	0.95	KDM4E (0.43)	MMP9KDM4ETP53MAPTTSHR
	SCHEMBL24315267	0.94	KDM4E (0.46)	MMP9KDM4ETP53MAPTTSHR
	SCHEMBL12580374	0.94	MMP2 (0.50)	MMP9KDM4ETP53MAPTTSHR
	SCHEMBL12580425	0.94	MMP2 (0.50)	MMP9KDM4ETP53MAPTTSHR
	SCHEMBL19166596	0.93	CKS1B (0.40)	MMP9KDM4ETP53MAPTTSHR
	SCHEMBL12580384	0.92	KDM4E (0.46)	MMP9KDM4ETP53MAPTTSHR
	SCHEMBL12580439	0.92	KDM4E (0.46)	MMP9KDM4ETP53MAPTTSHR
	SCHEMBL12580382	0.92	MMP2 (0.48)	MMP9KDM4ETP53MAPTTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.