Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.59 |
| ▸ | TTK | P33981 | 4/20 | 0.56 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.54 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.54 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.54 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.54 |
| ▸ | CSF1R | P07333 | 1/20 | 0.54 |
| ▸ | FER | P16591 | 1/20 | 0.54 |
| ▸ | CDK2 | P24941 | 1/20 | 0.54 |
| ▸ | MARK3 | P27448 | 1/20 | 0.54 |
| ▸ | FLT4 | P35916 | 1/20 | 0.54 |
| ▸ | FLT3 | P36888 | 1/20 | 0.54 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.54 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.54 |
| ▸ | CLK2 | P49760 | 1/20 | 0.54 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.54 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.54 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.54 |
| ▸ | STK3 | Q13188 | 1/20 | 0.54 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11836042 | 0.90 | MAP4K4 (0.65) | MKNK1TTKDCLK1PRKD3MAP4K4 | |
| SCHEMBL17306477 | 0.87 | MKNK1 (0.76) | MKNK1TTKDCLK1PRKD3MAP4K4 | |
| SCHEMBL17829688 | 0.83 | PDPK1 (0.57) | MKNK1CDK2MAPK9JAK2KDM4E | |
| SCHEMBL17829681 | 0.83 | DCLK1 (0.60) | MKNK1TTKDCLK1PRKD3MAP4K4 | |
| SCHEMBL18977088 | 0.82 | TTK (0.75) | MKNK1TTKDCLK1PRKD3MAP4K4 | |
| SCHEMBL19597646 | 0.80 | TTK (0.72) | MKNK1TTKDCLK1PRKD3MAP4K4 | |
| SCHEMBL17306449 | 0.80 | MKNK1 (0.87) | MKNK1TTKDCLK1PRKD3MAP4K4 | |
| SCHEMBL10535374 | 0.77 | MKNK1 (0.61) | MKNK1JAK2HTR2AMAPK1MAP2K4 | |
| SCHEMBL17829693 | 0.76 | HTR2A (0.46) | MKNK1TTKDCLK1PRKD3MAP4K4 | |
| SCHEMBL17829687 | 0.76 | IDO1 (0.47) | MKNK1TTKDCLK1PRKD3MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160168140-A1 | HETEROCYCLIC COMPOUNDS AS ANTIBIOTIC POTENTIATORS | SYNERECA PHARMACEUTICALS (US) | 2016-06-16 | — | — | US | disclosed |
| US-20160168140-A1 | HETEROCYCLIC COMPOUNDS AS ANTIBIOTIC POTENTIATORS | SYNERECA PHARMACEUTICALS (US) | 2016-06-16 | — | — | US | disclosed |
| WO-2016094730-A1 | HETEROCYCLIC COMPOUNDS AS ANTIBIOTIC POTENTIATORS | SYNERECA PHARMACEUTICALS, INC. (US) | 2016-06-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160168140-A1 | HETEROCYCLIC COMPOUNDS AS ANTIBIOTIC POTENTIATORS | FOS, FOSB, YAP1 | MKNK1 1586/4885TTK 2038/4885DCLK1 3274/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.