Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K4 | P45985 | 1/20 | 0.71 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | RORC | P51449 | 4/20 | 0.42 |
| ▸ | UBE2N | P61088 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | RORB | Q92753 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1513019 | 0.87 | MAP2K4 (0.63) | MAP2K4LMNAALDH1A1NPSR1KMT2A | |
| SCHEMBL22801731 | 0.83 | MAP2K4 (1.00) | MAP2K4CYP1A2CYP2C9CYP2C19PTGER1 | |
| SCHEMBL6375104 | 0.82 | MAP2K4 (0.58) | MAP2K4LMNANPSR1RXFP1MEN1 | |
| SCHEMBL22801565 | 0.81 | MAP2K4 (0.62) | MAP2K4LMNAALDH1A1KMT2ARORC | |
| SCHEMBL22801675 | 0.81 | MAP2K4 (0.72) | MAP2K4RORCCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL29057628 | 0.78 | MAP2K4 (0.50) | MAP2K4LMNAALDH1A1KMT2ANPC1 | |
| SCHEMBL22801706 | 0.78 | MAP2K4 (0.68) | MAP2K4MEN1KMT2ARORCMAPT | |
| SCHEMBL6370616 | 0.77 | MAP2K4 (0.57) | MAP2K4RORCMAPTCYP1A2CYP2C9 | |
| SCHEMBL1513042 | 0.76 | MAP2K4 (0.48) | MAP2K4LMNAALDH1A1KMT2ARORC | |
| SCHEMBL17322872 | 0.75 | ALDH1A1 (0.71) | MAP2K4LMNAALDH1A1NPSR1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160168140-A1 | HETEROCYCLIC COMPOUNDS AS ANTIBIOTIC POTENTIATORS | SYNERECA PHARMACEUTICALS (US) | 2016-06-16 | — | — | US | disclosed |
| US-20160168140-A1 | HETEROCYCLIC COMPOUNDS AS ANTIBIOTIC POTENTIATORS | SYNERECA PHARMACEUTICALS (US) | 2016-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160168140-A1 | HETEROCYCLIC COMPOUNDS AS ANTIBIOTIC POTENTIATORS | FOS, FOSB, YAP1 | MAP2K4 793/4885LMNA 2074/4885ALDH1A1 4840/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.