Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.48 |
| ▸ | BCAT2 | O15382 | 2/20 | 0.44 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.43 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.43 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL1782498 | 0.95 | ALKBH1 (0.44) | ALKBH1BCAT2KCNQ3KCNQ2P4HTM | |
| SCHEMBL2063619 | 0.93 | ALKBH1 (0.50) | ALKBH1BCAT2KCNQ3KCNQ2P4HTM | |
| Hydrochloric Acid SCHEMBL2063475 | 0.92 | ALKBH1 (0.49) | ALKBH1BCAT2KCNQ3KCNQ2P4HTM | |
| SCHEMBL4085016 | 0.83 | HTR1F (0.50) | KCNQ3KCNQ2P4HTMRAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL4091202 | 0.82 | HTR1F (0.49) | KCNQ3KCNQ2P4HTMRAB9ANPC1 | |
| SCHEMBL4084213 | 0.81 | KCNQ3 (0.49) | KCNQ3KCNQ2P4HTMRAB9AKMT2A | |
| SCHEMBL4089385 | 0.81 | KMT2A (0.43) | RAB9ANPC1KMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL4094577 | 0.81 | KMT2A (0.43) | RAB9ANPC1KMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL4086359 | 0.81 | KCNQ3 (0.48) | KCNQ3KCNQ2P4HTMRAB9AKMT2A | |
| SCHEMBL4090589 | 0.80 | KCNQ3 (0.56) | KCNQ3KCNQ2RAB9ANPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110118268-A1 | NOVEL 1,4-DIAZA-BICYCLO[3.2.1]OCTANE DERIVATIVES USEFUL AS NICOTINIC ACETYLCHOLINE RECEPTOR MODULATORS | NEUROSEARCH A/S (DK) | 2011-05-19 | — | — | US | claimed |
| US-20110118268-A1 | NOVEL 1,4-DIAZA-BICYCLO[3.2.1]OCTANE DERIVATIVES USEFUL AS NICOTINIC ACETYLCHOLINE RECEPTOR MODULATORS | NEUROSEARCH A/S (DK) | 2011-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110118268-A1 | NOVEL 1,4-DIAZA-BICYCLO[3.2.1]OCTANE DERIVATIVES USEFUL AS NICOTINIC ACETYLCHOLINE RECEPTOR MODULATORS | CHRNA6, CHRNA2, CHRNA10 | ALKBH1 2314/4885BCAT2 2058/4885KCNQ3 807/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.