Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | HTR1A | P08908 | 3/20 | 0.41 |
| ▸ | HTR1F | P30939 | 3/20 | 0.41 |
| ▸ | HTR1B | P28222 | 2/20 | 0.41 |
| ▸ | HTR1D | P28221 | 2/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | FPR2 | P25090 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PLEC | Q15149 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4094577 | 0.99 | KMT2A (0.43) | KMT2AUSP2CYP11B1CYP11B2MEN1 | |
| SCHEMBL4085016 | 0.91 | HTR1F (0.50) | KMT2ACYP11B1CYP11B2MEN1HTR1A | |
| Hydrochloric Acid SCHEMBL4091202 | 0.89 | HTR1F (0.49) | CYP11B1CYP11B2HTR1AHTR1FHTR1B | |
| SCHEMBL4084213 | 0.88 | KCNQ3 (0.49) | KMT2ACYP11B1CYP11B2HTR1AHTR1F | |
| SCHEMBL2063619 | 0.88 | ALKBH1 (0.50) | KMT2AKDM4ENPC1RAB9A | |
| Hydrochloric Acid SCHEMBL4086359 | 0.87 | KCNQ3 (0.48) | KMT2ACYP11B1CYP11B2HTR1AHTR1F | |
| Hydrochloric Acid SCHEMBL2063475 | 0.87 | ALKBH1 (0.49) | KMT2AKDM4ENPC1RAB9A | |
| SCHEMBL4095142 | 0.87 | RAB9A (0.44) | KMT2AMEN1KDM4EALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4085314 | 0.86 | RAB9A (0.43) | KMT2AMEN1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL4079918 | 0.85 | KMT2A (0.50) | KMT2AMEN1POLBKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090197872-A1 | NOVEL 1,4-DIAZA-BICYCLO[3.2.2]NONYL PYRIMIDINYL DERIVATIVES AND THEIR MEDICAL USE | NEUROSEARCH A/S (DK) | 2009-08-06 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090197872-A1 | NOVEL 1,4-DIAZA-BICYCLO[3.2.2]NONYL PYRIMIDINYL DERIVATIVES AND THEIR MEDICAL USE | CHRNA2, CHRNA6, CHRNA3 | KMT2A 2614/4885USP2 4218/4885CYP11B1 1189/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.