Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 3/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | ACP1 | P24666 | 1/20 | 0.34 |
| ▸ | ABCG2 | Q9UNQ0 | 6/20 | 0.34 |
| ▸ | NT5E | P21589 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | USP1 | O94782 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17833277 | 0.90 | SYK (0.37) | SYKKDM4EALDH1A1GAARAD52 | |
| SCHEMBL17829897 | 0.90 | RAD52 (0.47) | ALDH1A1RAD52KMT2AKCNH2 | |
| SCHEMBL17833146 | 0.85 | USP1 (0.39) | SYKNR4A2RAD52KMT2AACP1 | |
| SCHEMBL17829898 | 0.83 | SYK (0.36) | SYKNR4A2RAD52KMT2ACTSK | |
| SCHEMBL17833144 | 0.83 | SMN1; SMN2 (0.47) | SYKNR4A2ALDH1A1GAARAD52 | |
| SCHEMBL17833152 | 0.82 | ACP1 (0.42) | SYKKDM4EALDH1A1GAARAD52 | |
| SCHEMBL17833235 | 0.81 | SYK (0.43) | SYKKDM4EALDH1A1GAARAD52 | |
| SCHEMBL17829910 | 0.81 | SYK (0.44) | SYKKDM4EALDH1A1GAARAD52 | |
| SCHEMBL17829579 | 0.80 | ALDH1A1 (0.53) | ALDH1A1RAD52KMT2AKCNH2ACP1 | |
| SCHEMBL17833238 | 0.80 | TNKS (0.41) | SYKKDM4EALDH1A1GAARAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016094730-A1 | HETEROCYCLIC COMPOUNDS AS ANTIBIOTIC POTENTIATORS | SYNERECA PHARMACEUTICALS, INC. (US) | 2016-06-16 | — | — | WO | disclosed |