SCHEMBL17833694

SCHEMBL17833694

CC(C)Cc1ccc(N(c2ccccc2)c2ccc3c(-c4ccccc4)c4cc(N(c5ccccc5)c5ccc(CC(C)C)cc5)ccc4c(-c4ccccc4)c3c2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 1/20 0.36
STAT3 P40763 1/20 0.34
ALOX5 P09917 2/20 0.34
DPP4 P27487 3/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
MME P08473 1/20 0.33
ACE P12821 1/20 0.33
POLB P06746 1/20 0.33
MAPT P10636 1/20 0.33
PTGS1 P23219 3/20 0.33
PTGS2 P35354 3/20 0.33
LMNA P02545 2/20 0.33
CYP2C9 P11712 2/20 0.33
AKR1C3 P42330 2/20 0.33
CXCR1 P25024 2/20 0.33
CXCR2 P25025 2/20 0.33
ALB P02768 1/20 0.33
ESR1 P03372 1/20 0.33
RARB P10826 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14401551 0.89 DHODH (0.39) DHODHALOX5DPP4MEN1KMT2A
SCHEMBL17833690 0.85 TP53 (0.39) MEN1KMT2AMAPTCYP2C9KDM4E
SCHEMBL13886632 0.83 ALDH1A1 (0.43) MEN1KMT2AMAPTLMNACYP2C9
SCHEMBL195669 0.83 ALDH1A1 (0.43) MEN1KMT2AMAPTLMNACYP2C9
SCHEMBL17833692 0.83 MCL1 (0.35) STAT3MEN1KMT2AMAPTCYP2C9
SCHEMBL4650027 0.82 L3MBTL1 (0.42) MEN1KMT2APOLBMAPTLMNA
SCHEMBL36956 0.82 L3MBTL1 (0.42) MEN1KMT2APOLBMAPTLMNA
SCHEMBL19670682 0.82 CYP2C9 (0.45) ALOX5MEN1KMT2AMAPTPTGS1
SCHEMBL17833695 0.81 ALDH1A1 (0.38) DHODHDPP4MEN1KMT2AMAPT
SCHEMBL17833691 0.81 HSD11B1 (0.43) DHODHSTAT3RARBALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210104680-A1 ORGANIC ELECTROLUMINESCENT ELEMINT, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2021-04-08 US disclosed
US-10910565-B2 Organic electroluminescent element, material for organic electroluminescent elements, and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2021-02-02 US disclosed
US-20160211462-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, AND ELECTRONIC DEVICE IDEMIRSU KOSAN CO., LTD. (JP) 2016-07-21 US disclosed
US-20160211462-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, AND ELECTRONIC DEVICE IDEMIRSU KOSAN CO., LTD. (JP) 2016-07-21 US disclosed
US-20160172602-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2016-06-16 US disclosed
US-20160172602-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2016-06-16 US disclosed