Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 16/20 | 0.67 |
| ▸ | POLB | P06746 | 14/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 14/20 | 0.67 |
| ▸ | MEN1 | O00255 | 14/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 14/20 | 0.67 |
| ▸ | RECQL | P46063 | 13/20 | 0.67 |
| ▸ | USP2 | O75604 | 12/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.67 |
| ▸ | BLM | P54132 | 10/20 | 0.67 |
| ▸ | THRB | P10828 | 8/20 | 0.67 |
| ▸ | APEX1 | P27695 | 7/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.67 |
| ▸ | HPGD | P15428 | 5/20 | 0.67 |
| ▸ | NSD2 | O96028 | 4/20 | 0.67 |
| ▸ | PTPN22 | Q9Y2R2 | 2/20 | 0.67 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.67 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.67 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.61 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17834314 | 0.88 | MEN1 (0.63) | MAPTPOLBL3MBTL1MEN1KMT2A | |
| SCHEMBL14680229 | 0.76 | MAPT (1.00) | MAPTPOLBL3MBTL1MEN1KMT2A | |
| SCHEMBL8172936 | 0.74 | MAPT (0.64) | MAPTPOLBL3MBTL1MEN1KMT2A | |
| SCHEMBL19419942 | 0.73 | MAPT (0.83) | MAPTPOLBL3MBTL1MEN1KMT2A | |
| SCHEMBL26459002 | 0.72 | MAPT (1.00) | MAPTPOLBL3MBTL1MEN1KMT2A | |
| SCHEMBL26485785 | 0.71 | MAPT (0.65) | MAPTPOLBL3MBTL1MEN1KMT2A | |
| SCHEMBL26458902 | 0.70 | MAPT (1.00) | MAPTPOLBL3MBTL1MEN1KMT2A | |
| SCHEMBL14680220 | 0.70 | MAPT (1.00) | MAPTPOLBL3MBTL1MEN1KMT2A | |
| SCHEMBL17229211 | 0.69 | KMT2A (0.82) | MAPTPOLBL3MBTL1MEN1KMT2A | |
| SCHEMBL6886015 | 0.67 | MAPT (0.88) | MAPTPOLBL3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10017520-B2 | Myc modulators and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2018-07-10 | — | — | US | disclosed |
| US-20160168165-A1 | MYC MODULATORS AND USES THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160168165-A1 | MYC MODULATORS AND USES THEREOF | MYC, MYCBP, MYCBP2 | MAPT 2226/4885POLB 2076/4885L3MBTL1 2422/4885 |
| US-10017520-B2 | Myc modulators and uses thereof | MYC, MYCBP, MYCBP2 | MAPT 2226/4885POLB 2076/4885L3MBTL1 2422/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.