Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 15/20 | 1.00 |
| ▸ | MEN1 | O00255 | 14/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 14/20 | 1.00 |
| ▸ | POLB | P06746 | 13/20 | 1.00 |
| ▸ | L3MBTL1 | Q9Y468 | 12/20 | 1.00 |
| ▸ | RECQL | P46063 | 12/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 1.00 |
| ▸ | LMNA | P02545 | 3/20 | 1.00 |
| ▸ | HTT | P42858 | 3/20 | 1.00 |
| ▸ | RAB9A | P51151 | 2/20 | 1.00 |
| ▸ | NPC1 | O15118 | 1/20 | 1.00 |
| ▸ | USP2 | O75604 | 10/20 | 0.80 |
| ▸ | BLM | P54132 | 8/20 | 0.80 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.80 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.71 |
| ▸ | APEX1 | P27695 | 6/20 | 0.63 |
| ▸ | MCL1 | Q07820 | 6/20 | 0.63 |
| ▸ | ALPL | P05186 | 4/20 | 0.63 |
| ▸ | ALPI | P09923 | 2/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2985626 | 0.84 | MEN1 (0.76) | MAPTMEN1KMT2APOLBL3MBTL1 | |
| SCHEMBL8172936 | 0.77 | MAPT (0.64) | MAPTMEN1KMT2APOLBL3MBTL1 | |
| SCHEMBL5993381 | 0.73 | MEN1 (0.60) | MAPTMEN1KMT2APOLBL3MBTL1 | |
| SCHEMBL26485785 | 0.73 | MAPT (0.65) | MAPTMEN1KMT2APOLBL3MBTL1 | |
| SCHEMBL5991599 | 0.72 | MEN1 (0.75) | MAPTMEN1KMT2APOLBL3MBTL1 | |
| SCHEMBL17833967 | 0.72 | MAPT (0.67) | MAPTMEN1KMT2APOLBL3MBTL1 | |
| SCHEMBL3012532 | 0.71 | MEN1 (1.00) | MAPTMEN1KMT2APOLBL3MBTL1 | |
| SCHEMBL17229211 | 0.71 | KMT2A (0.82) | MAPTMEN1KMT2APOLBL3MBTL1 | |
| SCHEMBL17834314 | 0.70 | MEN1 (0.63) | MAPTMEN1KMT2APOLBL3MBTL1 | |
| SCHEMBL14680208 | 0.69 | MAPT (1.00) | MAPTMEN1KMT2APOLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230364057-A1 | BACTERIAL DNA GYRASE INHIBITORS AND METHODS OF USE THEREOF | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. | 2023-11-16 | — | — | US | disclosed |
| US-20230364057-A1 | BACTERIAL DNA GYRASE INHIBITORS AND METHODS OF USE THEREOF | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. | 2023-11-16 | — | — | US | disclosed |
| US-20230136466-A1 | BACTERIAL DNA GYRASE INHIBITORS AND METHODS OF USE THEREOF | THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (US) | 2023-05-04 | — | — | US | disclosed |
| US-20230136466-A1 | BACTERIAL DNA GYRASE INHIBITORS AND METHODS OF USE THEREOF | THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (US) | 2023-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230364057-A1 | BACTERIAL DNA GYRASE INHIBITORS AND METHODS OF USE THEREOF | TOP1, DNA2, TOP2A | MAPT 3260/4885MEN1 4457/4885KMT2A 2037/4885 |
| US-20230136466-A1 | BACTERIAL DNA GYRASE INHIBITORS AND METHODS OF USE THEREOF | TOP1, DNA2, TOP2A | MAPT 3260/4885MEN1 4457/4885KMT2A 2037/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.