Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | THRB | P10828 | 2/20 | 0.47 |
| ▸ | GFER | P55789 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28271336 | 0.88 | ELANE (0.50) | RAB9AHPGDKMT2AMEN1ALDH1A1 | |
| SCHEMBL1263952 | 0.86 | THRB (0.54) | RAB9AHPGDNPC1KMT2AMEN1 | |
| SCHEMBL4526045 | 0.85 | HPGD (0.61) | RAB9AHPGDNPC1KMT2AMEN1 | |
| SCHEMBL21467140 | 0.82 | ALDH1A1 (0.46) | RAB9AHPGDNPC1KMT2AMEN1 | |
| SCHEMBL13586656 | 0.79 | ELANE (0.45) | HPGDKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL8835461 | 0.79 | ELANE (0.56) | RAB9ANPC1KMT2ATHRBSMN1; SMN2 | |
| SCHEMBL39494 | 0.78 | ELANE (0.65) | NPC1KMT2AMEN1ALDH1A1THRB | |
| Trimethylammonium SCHEMBL28842333 | 0.78 | THRB (0.51) | RAB9AHPGDKMT2AMEN1ALDH1A1 | |
| SCHEMBL21657894 | 0.78 | NPC1 (0.53) | RAB9ANPC1KMT2AMEN1ALDH1A1 | |
| SCHEMBL11556448 | 0.78 | MAPT (0.50) | RAB9AHPGDNPC1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10444249-B2 | Ion sensor | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2019-10-15 | — | — | US | disclosed |
| US-20160169920-A1 | ION SENSOR | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2016-06-16 | — | — | US | disclosed |
| US-20160169920-A1 | ION SENSOR | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2016-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160169920-A1 | ION SENSOR | ORAI1, CACNA1E, NCS1 | RAB9A 2127/4885HPGD 4752/4885NPC1 4556/4885 |
| US-10444249-B2 | Ion sensor | ORAI1, NCS1, CACNA1E | RAB9A 1795/4885HPGD 4835/4885NPC1 4122/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.