SCHEMBL17467256

SCHEMBL17467256

CCc1nc(CC)nc(-c2cccc(-c3ccc(-c4ccccc4)cc3)c2)n1

nearest known ligand 0.45

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PDE4B Q07343 11/20 0.43
PDE4D Q08499 8/20 0.43
BCL2 P10415 1/20 0.42
GP6 Q9HCN6 1/20 0.42
KMO O15229 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26083938 0.95 PDE4B (0.44) PDE4BPDE4DBCL2GP6KMO
SCHEMBL23775951 0.93 L3MBTL1 (0.47) PDE4BPDE4DBCL2GP6KMO
SCHEMBL23776021 0.89 HSD17B1 (0.44) PDE4BPDE4DBCL2
SCHEMBL22376564 0.88 SMN1; SMN2 (0.44) PDE4BPDE4D
SCHEMBL23775950 0.85 L3MBTL1 (0.54)
SCHEMBL28827877 0.85 L3MBTL1 (0.52)
SCHEMBL17834290 0.83 PRMT6 (0.45) PDE4BPDE4D
SCHEMBL25680707 0.83 CYP11B1 (0.38) PDE4BPDE4D
SCHEMBL25680699 0.83 CYP11B1 (0.38) PDE4BPDE4DBCL2
SCHEMBL23776068 0.81 MEN1 (0.47) PDE4BPDE4D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230130110-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-04-27 US disclosed
US-20160028021-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2016-01-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160028021-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, OR10J3 PDE4B 3866/4885PDE4D 3867/4885BCL2 3252/4885
US-20230130110-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES SOD1, PIEZO1, L1CAM PDE4B 4576/4885PDE4D 4800/4885BCL2 2898/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.