Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 7/20 | 0.40 |
| ▸ | ACE | P12821 | 5/20 | 0.40 |
| ▸ | ACE2 | Q9BYF1 | 5/20 | 0.40 |
| ▸ | KIFC1 | Q9BW19 | 2/20 | 0.39 |
| ▸ | CPA1 | P15085 | 4/20 | 0.38 |
| ▸ | HPGDS | O60760 | 1/20 | 0.38 |
| ▸ | ITGB1 | P05556 | 8/20 | 0.38 |
| ▸ | ITGA4 | P13612 | 7/20 | 0.38 |
| ▸ | ITGB7 | P26010 | 6/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGAV | P06756 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.38 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.38 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.36 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15019919 | 0.92 | MME (0.42) | MMEACEACE2KIFC1CPA1 | |
| SCHEMBL15019922 | 0.92 | MME (0.42) | MMEACEACE2KIFC1CPA1 | |
| SCHEMBL17459538 | 0.84 | ITGA4 (0.42) | MMEACEACE2KIFC1CPA1 | |
| SCHEMBL17459539 | 0.84 | ITGA4 (0.42) | MMEACEACE2KIFC1CPA1 | |
| SCHEMBL17459639 | 0.83 | MME (0.41) | MMEHPGDS | |
| SCHEMBL17459640 | 0.83 | MME (0.41) | MMEHPGDS | |
| SCHEMBL16295098 | 0.83 | MME (0.41) | MMEHPGDS | |
| SCHEMBL17968819 | 0.83 | HPGDS (0.35) | MMEACEACE2KIFC1HPGDS | |
| SCHEMBL17459565 | 0.83 | HPGDS (0.35) | MMEACEACE2KIFC1HPGDS | |
| SCHEMBL22449251 | 0.82 | KIFC1 (0.43) | MMEACEACE2KIFC1CPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016094729-A1 | GLP-1 RECEPTOR MODULATORS | CELGENE INTERNATIONAL II SARL (CH) | 2016-06-16 | — | — | WO | disclosed |