SCHEMBL1783491

SCHEMBL1783491

CCCC(C)(OC)C(C)=CC(C)=O

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.32
HSD17B10 Q99714 1/20 0.32
GAA P10253 1/20 0.32
ELANE P08246 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1783490 1.00 LMNA (0.32) LMNAHSD17B10GAAELANE
SCHEMBL1783241 0.89 ALDH1A1 (0.35) GAA
SCHEMBL1783243 0.89 ALDH1A1 (0.35) GAA
SCHEMBL1783549 0.84 ALDH1A1 (0.32) GAA
SCHEMBL1783551 0.84 ALDH1A1 (0.32) GAA
SCHEMBL1785734 0.77 GAA (0.48) LMNAHSD17B10GAAELANE
SCHEMBL1784306 0.74 FDPS (0.32) LMNAHSD17B10
SCHEMBL1784304 0.74 FDPS (0.32) LMNAHSD17B10
SCHEMBL1739828 0.73 LMNA (0.38) LMNAHSD17B10GAAELANE
SCHEMBL7031959 0.73 LMNA (0.38) LMNAHSD17B10GAAELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8632792-B2 Cooling sensation agent composition and sensory stimulation agent composition TAKASAGO INTERNATIONAL CORPORATION (JP) 2014-01-21 US disclosed
US-20110117147-A1 COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION TAKASAGO INTERNATIONAL CORPORATION (JP) 2011-05-19 US disclosed
WO-2009123355-A2 COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION TAKASAGO INTERNATIONAL CORPORATION (JP) 2009-10-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110117147-A1 COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION TRPA1, HRH1, HRH2 LMNA 1708/4885HSD17B10 2048/4885GAA 4800/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.