Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | HTT | P42858 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | F9 | P00740 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 5/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.41 |
| ▸ | TNF | P01375 | 1/20 | 0.39 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.39 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17835177 | 0.78 | F9 (0.50) | F9RPS6KB1AKT1AURKBINCENP | |
| SCHEMBL17825660 | 0.72 | F9 (0.41) | ALDH1A1MAPTLMNAMEN1KMT2A | |
| SCHEMBL29031389 | 0.69 | KCNA5 (0.40) | ALDH1A1HTTSMN1; SMN2TDP1NPSR1 | |
| SCHEMBL21889466 | 0.68 | ALDH1A1 (0.55) | ALDH1A1HTTMAPTSMN1; SMN2TDP1 | |
| SCHEMBL27502430 | 0.66 | LMNA (0.57) | ALDH1A1HTTSMN1; SMN2TDP1NPSR1 | |
| SCHEMBL17825867 | 0.64 | TAAR1 (0.39) | ALDH1A1HTTMAPTSMN1; SMN2TDP1 | |
| SCHEMBL21574585 | 0.64 | KCNA5 (0.45) | ALDH1A1HTTSMN1; SMN2NPSR1LMNA | |
| SCHEMBL5655555 | 0.64 | L3MBTL1 (0.51) | ALDH1A1HTTMAPTSMN1; SMN2TDP1 | |
| SCHEMBL29894681 | 0.63 | GAA (0.44) | ALDH1A1HTTMAPTSMN1; SMN2TDP1 | |
| SCHEMBL28889353 | 0.63 | GAA (0.44) | ALDH1A1HTTMAPTSMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016094260-A1 | FACTOR IXA INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2016-06-16 | — | — | WO | disclosed |