Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | PAOX | Q6QHF9 | 4/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | GABRP | O00591 | 2/20 | 0.31 |
| ▸ | GABRD | O14764 | 2/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.31 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.31 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1781677 | 0.93 | PAOX (0.44) | ALDH1A1PAOXACHECHRNB2CHRNB4 | |
| SCHEMBL15943069 | 0.85 | ALDH1A1 (0.43) | ALDH1A1PAOXACHECHRNB2CHRNB4 | |
| SCHEMBL237372 | 0.84 | ALDH1A1 (0.47) | ALDH1A1PAOXACHECHRNB2CHRNB4 | |
| SCHEMBL16360132 | 0.84 | ALDH1A1 (0.47) | ALDH1A1PAOXACHECHRNB2CHRNB4 | |
| SCHEMBL16786175 | 0.84 | ALDH1A1 (0.47) | ALDH1A1PAOXACHECHRNB2CHRNB4 | |
| SCHEMBL23396422 | 0.81 | PAOX (0.43) | ALDH1A1PAOXACHECHRNB2CHRNB4 | |
| SCHEMBL1783122 | 0.81 | ALDH1A1 (0.39) | ALDH1A1PAOXACHECHRNB2CHRNB4 | |
| SCHEMBL20489977 | 0.80 | CHRNB2 (0.39) | CHRNB2CHRNB4CHRNA4CA1GABRP | |
| SCHEMBL20129391 | 0.80 | PAOX (0.52) | ALDH1A1PAOXACHETDP1LMNA | |
| SCHEMBL18222768 | 0.80 | LMNA (0.48) | ALDH1A1TDP1LMNAGABRPGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8632792-B2 | Cooling sensation agent composition and sensory stimulation agent composition | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2014-01-21 | — | — | US | disclosed |
| US-20110117147-A1 | COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2011-05-19 | — | — | US | disclosed |
| WO-2009123355-A2 | COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2009-10-08 | — | — | WO | disclosed |
| US-4254038-A | ODORS; PERFUMES; FOR COMPLEXING SOLVENTS | ETHYL CORPORATION (US) | 1981-03-03 | — | — | US | disclosed |
| US-4254037-A | FOR PERFUMES, ODORANTS, COMPLEXING SOLVENTS | ETHYL CORPORATION (US) | 1981-03-03 | — | — | US | disclosed |
| US-4212812-A | TREATING AN ALKENOL WITH A STRONG ACID TO EFFECT CYCLIZATION | ETHYL CORPORATION (US) | 1980-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110117147-A1 | COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION | TRPA1, HRH1, HRH2 | ALDH1A1 520/4885PAOX 2315/4885ACHE 1079/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.