Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8369723 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL6560628 | 0.74 | GPR3 (0.30) | — | |
| Hydrochloric Acid SCHEMBL7199565 | 0.68 | HTR6 (0.30) | — | |
| SCHEMBL7200575 | 0.65 | HTR6 (0.30) | — | |
| Hydrochloric Acid SCHEMBL3368197 | 0.65 | — | — | |
| Hydrochloric Acid SCHEMBL16394143 | 0.63 | HTR6 (0.32) | — | |
| Hydrochloric Acid SCHEMBL7204700 | 0.63 | — | — | |
| SCHEMBL1080492 | 0.61 | SIGMAR1 (0.33) | — | |
| Hydrochloric Acid SCHEMBL812668 | 0.61 | HTR2A (0.40) | — | |
| SCHEMBL27460809 | 0.61 | HTR2A (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3237461-B1 | PROCESS FOR THE PREPARATION OF A POLYOLEFIN HAVING ONE OR MULTIPLE END-FUNCTIONALIZED BRANCHES | SABIC GLOBAL TECHNOLOGIES BV (NL) | 2026-03-18 | — | — | EP | disclosed |
| EP-3034545-B1 | A PROCESS FOR THE PREPARATION OF A GRAFT COPOLYMER COMPRISING A POLYOLEFIN MAIN CHAIN AND ONE OR A MULTIPLE POLYMER SIDE CHAINS AND THE PRODUCTS OBTAINED THEREFROM | SABIC GLOBAL TECHNOLOGIES BV (NL) | 2020-11-04 | — | — | EP | disclosed |
| US-10787545-B2 | Process for the preparation of polyolefin-based graft copolymers comprising a first functionalized short chain branched polyolefin block and one or multiple polymer side chains | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2020-09-29 | — | — | US | disclosed |
| US-20200262983-A1 | PROCESS FOR THE PREPARATION OF POLYOLEFIN-BASED GRAFT COPOLYMERS COMPRISING A FIRST FUNCTIONALIZED SHORT CHAIN BRANCHED POLYOLEFIN BLOCK AND ONE OR MULTIPLE POLYMER SIDE CHAINS | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2020-08-20 | — | — | US | disclosed |
| US-10717826-B2 | Process for the preparation of polyolefin-based graft copolymers comprising a first long chain branched polyolefin block and one or multiple polymer side chains | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2020-07-21 | — | — | US | disclosed |
| EP-3233974-B1 | A PROCESS FOR THE PREPARATION OF A BLOCK COPOLYMER COMPRISING A FIRST POLYOLEFIN BLOCK AND A SECOND POLYMER BLOCK | SABIC GLOBAL TECHNOLOGIES BV (NL) | 2020-02-19 | — | — | EP | disclosed |
| US-10472447-B2 | Process for the preparation of a graft copolymer comprising a polyolefin main chain and one or a multiple polymer side chains and the products obtained therefrom | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2019-11-12 | — | — | US | disclosed |
| US-10465018-B2 | Process for the preparation of a polyolefin having one or multiple end-functionalized branches | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2019-11-05 | — | — | US | disclosed |
| US-10450388-B2 | Process for the preparation of a branched polyolefin | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2019-10-22 | — | — | US | disclosed |
| EP-3034546-B1 | A process for the preparation of a block copolymer comprising a first polyolefin block and a second polymer block | SABIC GLOBAL TECHNOLOGIES BV (NL) | 2019-10-16 | — | — | EP | disclosed |
| EP-3037438-A1 | Process for the preparation of a branched polyolefin | SABIC Global Technologies B.V. (NL) | 2016-06-29 | — | — | EP | disclosed |
| EP-3037437-A1 | Process for the preparation of a polyolefin having one or multiple end-functionalized branches. | SABIC Global Technologies B.V. (NL) | 2016-06-29 | — | — | EP | disclosed |
| WO-2016097204-A1 | A PROCESS FOR THE PREPARATION OF A GRAFT COPOLYMER COMPRISING A POLYOLEFIN MAIN CHAIN AND ONE OR A MULTIPLE POLYMER SIDE CHAINS AND THE PRODUCTS OBTAINED THEREFROM | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2016-06-23 | — | — | WO | disclosed |
| WO-2016097208-A1 | A PROCESS FOR THE PREPARATION OF A BLOCK COPOLYMER COMPRISING A FIRST POLYOLEFIN BLOCK AND A SECOND POLYMER BLOCK AND THE PRODUCTS OBTAINED THEREFROM | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2016-06-23 | — | — | WO | disclosed |
| WO-2016097207-A1 | A PROCESS FOR THE PREPARATION OF A GRAFT COPOLYMER COMPRISING A POLYOLEFIN MAIN CHAIN AND ONE OR A MULTIPLE POLYMER SIDE CHAINS AND THE PRODUCTS OBTAINED THEREFROM | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2016-06-23 | — | — | WO | disclosed |
| WO-2016097203-A1 | A PROCESS FOR THE PREPARATION OF A BLOCK COPOLYMER COMPRISING A FIRST POLYOLEFIN BLOCK AND A SECOND POLYMER BLOCK AS WELL AS THE PRODUCTS OBTAINED THEREFROM | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2016-06-23 | — | — | WO | disclosed |
| EP-3034545-A1 | A process for the preparation of a graft copolymer comprising a polyolefin main chain and one or a multiple polymer side chains and the products obtained therefrom | SABIC Global Technologies B.V. (NL) | 2016-06-22 | — | — | EP | disclosed |
| EP-3034546-A1 | A process for the preparation of a block copolymer comprising a first polyolefin block and a second polymer block as well as the products obtained therefrom | SABIC Global Technologies B.V. (NL) | 2016-06-22 | — | — | EP | disclosed |
| EP-3034547-A1 | A process for the preparation of a block copolymer comprising a first polyolefin block and a second polymer block and the products obtained therefrom | SABIC Global Technologies B.V. (NL) | 2016-06-22 | — | — | EP | disclosed |
| EP-3034544-A1 | A process for the preparation of a graft copolymer comprising a polyolefin main chain and one or a multiple polymer side chains and the products obtained therefrom | SABIC Global Technologies B.V. (NL) | 2016-06-22 | — | — | EP | disclosed |