SCHEMBL178367

SCHEMBL178367

CCCCNC(=O)c1ccc(C)cc1

nearest known ligand 0.87

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.87
LMNA P02545 1/20 0.66
POLB P06746 1/20 0.66
SMN1; SMN2 Q16637 3/20 0.64
NAAA Q02083 2/20 0.62
HPGD P15428 1/20 0.60
NPC1 O15118 5/20 0.58
RAB9A P51151 4/20 0.58
KMT2A Q03164 2/20 0.58
MLYCD O95822 1/20 0.58
ALDH1A1 P00352 2/20 0.58
TSHR P16473 1/20 0.58
HTT P42858 1/20 0.58
MEN1 O00255 1/20 0.57
MMP13 P45452 1/20 0.57
CA2 P00918 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15782158 0.95 L3MBTL1 (0.79) L3MBTL1LMNAPOLBSMN1; SMN2NAAA
SCHEMBL13577911 0.95 L3MBTL1 (0.97) L3MBTL1LMNAPOLBSMN1; SMN2NAAA
SCHEMBL24220267 0.93 L3MBTL1 (1.00) L3MBTL1LMNAPOLBSMN1; SMN2NAAA
SCHEMBL8208835 0.93 L3MBTL1 (1.00) L3MBTL1LMNAPOLBSMN1; SMN2NAAA
SCHEMBL7961787 0.93 L3MBTL1 (1.00) L3MBTL1LMNAPOLBSMN1; SMN2NAAA
SCHEMBL28326194 0.92 L3MBTL1 (0.73) L3MBTL1SMN1; SMN2NAAANPC1RAB9A
SCHEMBL9489979 0.89 L3MBTL1 (0.86) L3MBTL1LMNAPOLBSMN1; SMN2NAAA
SCHEMBL765958 0.89 L3MBTL1 (0.74) L3MBTL1LMNAPOLBSMN1; SMN2NPC1
SCHEMBL11220601 0.86 LMNA (0.85) L3MBTL1LMNAPOLBSMN1; SMN2NPC1
SCHEMBL22919705 0.85 L3MBTL1 (0.65) L3MBTL1SMN1; SMN2NAAANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115304506-B Preparation method of secondary amide compound by activating primary amide through boron salt catalysis 中国人民解放军国防科技大学 2023-11-14 CN disclosed
CN-115974711-A Preparation method of aryl amide compound by using aromatic ester catalytically activated by boron salt 湖南农业大学 2023-04-18 CN disclosed
CN-115304506-A Preparation method of secondary amide compound by activating primary amide under catalysis of boron salt 中国人民解放军国防科技大学 2022-11-08 CN disclosed
CN-104761420-B Method for synthesizing amide from methyl aromatic hydrocarbon and amine in water phase 江西师范大学 2021-03-05 CN disclosed
EP-3233041-B1 COSMETIC PROCESS FOR ATTENUATING WRINKLES OREAL (FR) 2019-01-30 EP disclosed
US-20170035893-A1 ISATOIC ANHYDRIDE DERIVATIVES AND APPLICATIONS THEREOF THE UNIVERSITY OF NORTH CAROLINA AT CHARLOTTE 2017-02-09 US disclosed
CN-104761420-A Method of synthesizing amide with methyl aromatics and amine in water phase UNIV JIANGXI NORMAL 2015-07-08 CN disclosed
US-8841249-B2 Growth hormones with prolonged in-vivo efficacy NOVO NORDISK A/S (DK) 2014-09-23 US disclosed
US-8703721-B2 Arylalkylamine compound and process for preparing the same MITSUBISHI TANABE PHARMA CORPORATION (JP) 2014-04-22 US disclosed
US-8703721-B2 Arylalkylamine compound and process for preparing the same MITSUBISHI TANABE PHARMA CORPORATION (JP) 2014-04-22 US disclosed
US-4160095-A PROSTAGLANDINS; ANTIINFLAMMATORY AGENTS THE UPJOHN COMPANY (US) 1979-07-03 US disclosed
US-4157441-A PROSTAGLANDINS, ANTIINFLAMMATORY AGENTS THE UPJOHN COMPANY (US) 1979-06-05 US disclosed
US-4151351-A PROSTAGLANDINS, ANTIINFLAMMATORY THE UPJOHN COMPANY (US) 1979-04-24 US disclosed
US-4131738-A 6-Hydroxy-PGE1 compounds THE UPJOHN COMPANY (US) 1978-12-26 US disclosed
US-4128713-A 6,7-Didehydro-PGI1 compounds THE UPJOHN COMPANY (US) 1978-12-05 US disclosed
US-4126744-A PROSTACYCLIN, MUSCLE STIMULANTS, PLATELET AGGREGATION INHIBITORS THE UPJOHN COMPANY (US) 1978-11-21 US disclosed
US-4112224-A PROSTAGLANDIN THE UPJOHN COMPANY (US) 1978-09-05 US disclosed
US-4109082-A PROSTACYCLIN ANALOGS; SMOOTH MUSCLE STIMULATORS THE UPJOHN COMPANY (US) 1978-08-22 US disclosed
US-4100192-A Inter-phenylene-PG amides THE UPJOHN COMPANY (US) 1978-07-11 US disclosed
US-4097489-A PROSTAGLANDINS THE UPJOHN COMPANY (US) 1978-06-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170035893-A1 ISATOIC ANHYDRIDE DERIVATIVES AND APPLICATIONS THEREOF AASDHPPT, CA13, CA12 L3MBTL1 4502/4885LMNA 1646/4885POLB 3431/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.