Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CRHR1 | P34998 | 10/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.31 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.31 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6015183 | 0.90 | ALDH1A1 (0.34) | ALDH1A1POLBMAPTHTTSMN1; SMN2 | |
| SCHEMBL23087150 | 0.89 | ALDH1A1 (0.35) | ALDH1A1POLBMAPTHTTSMN1; SMN2 | |
| SCHEMBL6015185 | 0.85 | ALDH1A1 (0.33) | ALDH1A1POLBMAPTHTTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL15333566 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL1007082 | 0.81 | TACR1 (0.31) | — | |
| Hydrochloric Acid SCHEMBL1007240 | 0.79 | — | — | |
| SCHEMBL19712595 | 0.77 | MEN1 (0.30) | CRHR1 | |
| SCHEMBL4608209 | 0.75 | — | — | |
| SCHEMBL15333568 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL15135074 | 0.73 | TAS1R3 (0.32) | ALDH1A1POLBMAPTHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10421702-B2 | Method for producing fluorine-containing olefin | AGC Inc. (JP) | 2019-09-24 | — | — | US | disclosed |
| US-20180086684-A1 | METHOD FOR PRODUCING FLUORINE-CONTAINING OLEFIN | ASAHI GLASS COMPANY, LIMITED (JP) | 2018-03-29 | — | — | US | disclosed |
| US-9796647-B2 | Method for producing fluorine-containing olefin | ASAHI GLASS COMPANY, LIMITED (JP) | 2017-10-24 | — | — | US | disclosed |
| US-20170101360-A1 | METHOD FOR PRODUCING FLUORINE-CONTAINING OLEFIN | ASAHI GLASS COMPANY, LIMITED (JP) | 2017-04-13 | — | — | US | disclosed |
| US-9598335-B2 | Method for producing fluorine-containing olefin | ASAHI GLASS COMPANY, LIMITED (JP) | 2017-03-21 | — | — | US | disclosed |
| EP-3042889-A1 | METHOD FOR PRODUCING FLUORINE-CONTAINING OLEFIN | Asahi Glass Company, Limited (JP) | 2016-07-13 | — | — | EP | disclosed |
| US-20160176791-A1 | METHOD FOR PRODUCING FLUORINE-CONTAINING OLEFIN | ASAHI GLASS COMPANY, LIMITED (JP) | 2016-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180086684-A1 | METHOD FOR PRODUCING FLUORINE-CONTAINING OLEFIN | FOS, CYP2F1, CYP4F11 | ALDH1A1 607/4885POLB 1860/4885MAPT 1704/4885 |
| US-10421702-B2 | Method for producing fluorine-containing olefin | FOS, CYP2F1, CYP4F11 | ALDH1A1 607/4885POLB 1860/4885MAPT 1704/4885 |
| US-20170101360-A1 | METHOD FOR PRODUCING FLUORINE-CONTAINING OLEFIN | FOS, CYP2F1, CYP4F11 | ALDH1A1 607/4885POLB 1860/4885MAPT 1704/4885 |
| US-20160176791-A1 | METHOD FOR PRODUCING FLUORINE-CONTAINING OLEFIN | FOS, CYP2F1, CYP4F11 | ALDH1A1 607/4885POLB 1860/4885MAPT 1704/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.