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SCHEMBL17836969

SCHEMBL17836969

CC(C)(C)OC(=O)c1cc(I)c(OC(=O)Oc2c(I)cc(C(=O)OC(C)(C)C)cc2I)c(I)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ELANE P08246 1/20 0.38
▸ TPMT P51580 2/20 0.37
▸ CA12 O43570 1/20 0.36
▸ CA1 P00915 1/20 0.36
▸ CA2 P00918 1/20 0.36
▸ CA9 Q16790 1/20 0.36
▸ CA14 Q9ULX7 1/20 0.36
▸ GABRG2 P18507 3/20 0.35
▸ GABRB3 P28472 3/20 0.35
▸ GABRA1 P14867 2/20 0.35
▸ GABRA3 P34903 2/20 0.35
▸ GABRA2 P47869 2/20 0.35
▸ ESR1 P03372 2/20 0.35
▸ SLC7A5 Q01650 1/20 0.35
▸ GABRA5 P31644 2/20 0.33
▸ MTNR1A P48039 1/20 0.33
▸ MTNR1B P49286 1/20 0.33
▸ BPTF Q12830 1/20 0.32
▸ STAT3 P40763 2/20 0.32
▸ ALOX15 P16050 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27297570 0.82 ESR1 (0.50) TPMTCA12CA1CA2CA9
SCHEMBL22991596 0.79 ELANE (0.41) ELANETPMTMTNR1AMTNR1BBPTF
SCHEMBL27280348 0.79 ELANE (0.43) ELANETPMTCA2GABRG2GABRB3
SCHEMBL27255792 0.78 ELANE (0.39) ELANETPMTESR1MTNR1AMTNR1B
SCHEMBL27255619 0.77 ELANE (0.42) ELANETPMTCA2MTNR1AMTNR1B
SCHEMBL7058435 0.77 CA12 (0.47) ELANECA12CA1CA2CA9
SCHEMBL14826122 0.76 MTNR1A (0.45) GABRA1GABRA2MTNR1AMTNR1BALOX15
SCHEMBL20920874 0.75 THRB (0.35) ELANETPMTALOX15
SCHEMBL12013026 0.74 APP (0.40) ELANEMTNR1AMTNR1B
SCHEMBL17854065 0.74 TPMT (0.58) TPMTCA12CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10087285-B2 Biocompatible iodinated diphenol monomers and polymers RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2018-10-02 — — US disclosed
EP-3237487-A2 BIOCOMPATIBLE IODINATED DIPHENOL MONOMERS AND POLYMERS Rutgers, the State University of New Jersey (US) 2017-11-01 — — EP disclosed
WO-2016103224-A2 BIOCOMPATIBLE IODINATED DIPHENOL MONOMERS AND POLYMERS RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2016-06-30 — — WO disclosed
WO-2016103224-A2 BIOCOMPATIBLE IODINATED DIPHENOL MONOMERS AND POLYMERS RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2016-06-30 — — WO disclosed
US-20160177028-A1 BIOCOMPATIBLE IODINATED DIPHENOL MONOMERS AND POLYMERS RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY 2016-06-23 — — US disclosed
US-20160177028-A1 BIOCOMPATIBLE IODINATED DIPHENOL MONOMERS AND POLYMERS RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY 2016-06-23 — — US disclosed
US-20160177028-A1 BIOCOMPATIBLE IODINATED DIPHENOL MONOMERS AND POLYMERS RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY 2016-06-23 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10087285-B2 Biocompatible iodinated diphenol monomers and polymers DDT, HPGDS, PTGDR ELANE 1298/4885TPMT 2599/4885CA12 2925/4885
US-20160177028-A1 BIOCOMPATIBLE IODINATED DIPHENOL MONOMERS AND POLYMERS DDT, HPGDS, PTGDR ELANE 1298/4885TPMT 2599/4885CA12 2925/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.