SCHEMBL178371

SCHEMBL178371

CC1(CC(=O)O)CCCCC1

nearest known ligand 0.54

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.54
CYP1A2 P05177 2/20 0.50
USP2 O75604 1/20 0.50
ALDH1A1 P00352 1/20 0.50
LMNA P02545 1/20 0.50
TSHR P16473 1/20 0.50
BLM P54132 1/20 0.50
CACNA2D1 P54289 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
HSD11B1 P28845 2/20 0.40
FFAR3 O14843 2/20 0.36
KMT2A Q03164 2/20 0.35
MAPK1 P28482 1/20 0.35
GABRA5 P31644 1/20 0.33
GABRB2 P47870 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15237486 1.00 CYP2C19 (0.54) CYP2C19CYP1A2USP2ALDH1A1LMNA
SCHEMBL6914857 0.98 CYP2C19 (0.52) CYP2C19CYP1A2USP2ALDH1A1LMNA
SCHEMBL6908133 0.98 CYP2C19 (0.52) CYP2C19CYP1A2USP2ALDH1A1LMNA
SCHEMBL6918554 0.98 CYP2C19 (0.52) CYP2C19CYP1A2USP2ALDH1A1LMNA
SCHEMBL6916767 0.98 CYP2C19 (0.52) CYP2C19CYP1A2USP2ALDH1A1LMNA
SCHEMBL6914937 0.98 CYP2C19 (0.52) CYP2C19CYP1A2USP2ALDH1A1LMNA
SCHEMBL6913148 0.98 CYP2C19 (0.52) CYP2C19CYP1A2USP2ALDH1A1LMNA
SCHEMBL6909533 0.98 CYP2C19 (0.52) CYP2C19CYP1A2USP2ALDH1A1LMNA
SCHEMBL6914861 0.98 CYP2C19 (0.52) CYP2C19CYP1A2USP2ALDH1A1LMNA
SCHEMBL1480296 0.97 CYP2C19 (0.50) CYP2C19CYP1A2USP2ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 304 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114790136-A Preparation method and application of active trivalent organic chromium compound 中国石油天然气股份有限公司 2022-07-26 CN claimed
US-20190016745-A1 AMINOGLYCOSIDE DERIVATIVES AND USES THEREOF IN TREATING MICROBIAL INFECTIONS TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) 2019-01-17 US claimed
EP-3400231-A1 AMINOGLYCOSIDE DERIVATIVES AND USES THEREOF IN TREATING MICROBIAL INFECTIONS Technion Research & Development Foundation Limited (IL) 2018-11-14 EP claimed
US-20180282361-A1 AMINOGLYCOSIDE DERIVATIVES AND USES THEREOF IN TREATING GENETIC DISORDERS ELOXX PHARMACEUTICALS LTD. (IL) 2018-10-04 US claimed
EP-3344641-A1 AMINOGLYCOSIDE DERIVATIVES AND USES THEREOF IN TREATING GENETIC DISORDERS Eloxx Pharmaceuticals Ltd. (IL) 2018-07-11 EP claimed
WO-2017118967-A1 AMINOGLYCOSIDE DERIVATIVES AND USES THEREOF IN TREATING MICROBIAL INFECTIONS TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) 2017-07-13 WO claimed
WO-2017037719-A1 AMINOGLYCOSIDE DERIVATIVES AND USES THEREOF IN TREATING GENETIC DISORDERS ELOXX PHARMACEUTICALS LTD. (IL) 2017-03-09 WO claimed
EP-2118052-A2 NOVEL PRODRUGS Sun Pharma Advanced Research Company Ltd (IN) 2009-11-18 EP claimed
WO-2008111096-A2 NOVEL PRODRUGS SUN PHARMA ADVANCED RESEARCH COMPANY LTD (IN) 2008-09-18 WO claimed
US-20030064972-A1 Materials and methods for the treatment of diabetes, hyperlipidemia, hypercholesterolemia, and atherosclerosis MPM ASSET MANAGEMENT INVESTORS 2002 BVIII LLC 2003-04-03 US claimed
US-12459882-B2 Process for preparing 1,2-propanediol from propane EVONIK OPERATIONS GMBH (DE) 2025-11-04 US disclosed
EP-4337603-B1 OPTIMIZED STEAM NETWORK FOR THE AO PROCESS EVONIK OPERATIONS GMBH (DE) 2025-04-09 EP disclosed
WO-2025072539-A1 AMINO ACID COMPOUNDS WITH NITROGEN LINKERS AND USES THEREOF PLIANT THERAPEUTICS, INC. (US) 2025-04-03 WO disclosed
EP-4337645-B1 AN INTEGRATED PLANT AND AN INTEGRATED PROCESS FOR MAKING PROPENE OXIDE EVONIK OPERATIONS GMBH (DE) 2025-03-12 EP disclosed
US-12102648-B2 Orally-bioavailable nucleoside analogs VenatoRx Pharmaceuticals, Inc. (US) 2024-10-01 US disclosed
US-3984393-A BACTERICIDES THE UPJOHN COMPANY (US) 1976-10-05 US disclosed
US-3976667-A ANTIBIOTIC THE UPJOHN COMPANY (US) 1976-08-24 US disclosed
US-3960762-A Production of absorbents BAYER AKTIENGESELLSCHAFT (DT) 1976-06-01 US disclosed
US-3945831-A Photosensitive resins containing a thienylacrylic acid ester or amide group FUJI PHOTO FILM CO., LTD. (JA) 1976-03-23 US disclosed
US-3944562-A ANTIBIOTIC THE UPJOHN COMPANY (US) 1976-03-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12102648-B2 Orally-bioavailable nucleoside analogs SLC29A2, SLC29A1, PNP CYP2C19 206/4885CYP1A2 387/4885USP2 2695/4885
US-20190016745-A1 AMINOGLYCOSIDE DERIVATIVES AND USES THEREOF IN TREATING MICROBIAL INFECTIONS ALPI, MGAM, AASDHPPT CYP2C19 902/4885CYP1A2 986/4885USP2 4664/4885
US-20030064972-A1 Materials and methods for the treatment of diabetes, hyperlipidemia, hypercholesterolemia, and atherosclerosis LIPA, LIPC, CETP CYP2C19 775/4885CYP1A2 254/4885USP2 860/4885
US-20180282361-A1 AMINOGLYCOSIDE DERIVATIVES AND USES THEREOF IN TREATING GENETIC DISORDERS UPF1, AARS1, NUDT21 CYP2C19 2439/4885CYP1A2 2733/4885USP2 4425/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.