Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | PTGES | O14684 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | IGF1R | P08069 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
| ▸ | AXL | P30530 | 1/20 | 0.31 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.31 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.31 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1785450 | 0.80 | SMN1; SMN2 (0.34) | ALDH1A1CYP3A4KDM4ENPSR1HTT | |
| SCHEMBL1787340 | 0.79 | HTT (0.33) | ALDH1A1CYP3A4POLBKDM4EHTT | |
| SCHEMBL1786027 | 0.74 | KMT2A (0.49) | ALDH1A1CYP3A4POLBRAB9ANPSR1 | |
| SCHEMBL7483142 | 0.72 | ALDH1A1 (0.33) | ALDH1A1CYP3A4PTGESPTPN1POLB | |
| SCHEMBL7477896 | 0.70 | MEN1 (0.33) | ALDH1A1POLBRAB9ANPSR1MEN1 | |
| SCHEMBL7479670 | 0.68 | MEN1 (0.36) | ALDH1A1CYP3A4PTGESPTPN1POLB | |
| SCHEMBL7482378 | 0.68 | ALDH1A1 (0.37) | ALDH1A1CYP3A4POLBKDM4ENPSR1 | |
| SCHEMBL7475018 | 0.68 | KDM4E (0.32) | ALDH1A1CYP3A4PTGESPTPN1POLB | |
| SCHEMBL7478512 | 0.67 | ALDH1A1 (0.33) | ALDH1A1POLBRAB9AKDM4ENPSR1 | |
| SCHEMBL7478089 | 0.67 | KDM4E (0.32) | ALDH1A1KDM4ENPSR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8273901-B2 | Process of forming a pyrrole compound | Nanyang Technical University (SG) | 2012-09-25 | — | — | US | disclosed |
| US-8273901-B2 | Process of forming a pyrrole compound | Nanyang Technical University (SG) | 2012-09-25 | — | — | US | disclosed |
| US-20110124881-A1 | PROCESS OF FORMING A PYRROLE COMPOUND | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2011-05-26 | — | — | US | disclosed |
| US-20110124881-A1 | PROCESS OF FORMING A PYRROLE COMPOUND | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2011-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110124881-A1 | PROCESS OF FORMING A PYRROLE COMPOUND | OXER1, OGDH, OPRD1 | ALDH1A1 67/4885CYP3A4 181/4885PTGES 425/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.