Acrylamide

Acrylamide

SCHEMBL17840598

C=CC(N)=O.C=CC(N)=O.C=CC(N)=O.CC(=CCCC[Si](O[Si](C)(C)C)(O[Si](C)(C)C)O[Si](C)(C)C)C(=O)O

nearest known ligand 0.31

Full drug profile on Sugi Atlas →

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.31
TSHR P16473 1/20 0.31
FGFR4 P22455 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL400292 0.90 TBXAS1 (0.33)
SCHEMBL809437 0.90 TBXAS1 (0.33)
SCHEMBL2474722 0.89 TDP1 (0.33)
SCHEMBL1802297 0.84 TBXAS1 (0.31)
SCHEMBL8466019 0.82 TBXAS1 (0.32)
SCHEMBL1803466 0.82 TBXAS1 (0.32)
SCHEMBL2121970 0.82 ALDH1A1 (0.31) ALDH1A1
SCHEMBL20597263 0.81 TBXAS1 (0.31)
SCHEMBL20596877 0.81 TBXAS1 (0.31)
SCHEMBL403240 0.80 CD81 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3390025-B1 REUSABLE LENS MOLDS AND METHODS OF USE THEREOF ALCON INC (CH) 2023-09-06 EP disclosed
EP-3233449-B1 REUSABLE LENS MOLDS AND METHODS OF USE THEREOF NOVARTIS AG (CH) 2019-07-24 EP disclosed
US-10328645-B2 Reusable lens molds and methods of use thereof NOVARTIS AG (CH) 2019-06-25 US disclosed
EP-3233450-B1 REUSABLE LENS MOLDS AND METHODS OF USE THEREOF NOVARTIS AG (CH) 2019-01-30 EP disclosed
EP-3390025-A1 REUSABLE LENS MOLDS AND METHODS OF USE THEREOF Novartis AG (CH) 2018-10-24 EP disclosed
US-9981436-B2 Reusable lens molds and methods of use thereof NOVARTIS AG (CH) 2018-05-29 US disclosed
US-9981435-B2 Reusable lens molds and methods of use thereof NOVARTIS AG (CH) 2018-05-29 US disclosed
EP-3233449-A1 REUSABLE LENS MOLDS AND METHODS OF USE THEREOF Novartis AG (CH) 2017-10-25 EP disclosed
EP-3233450-A1 REUSABLE LENS MOLDS AND METHODS OF USE THEREOF Novartis AG (CH) 2017-10-25 EP disclosed
US-20170173902-A1 REUSABLE LENS MOLDS AND METHODS OF USE THEREOF ALCON INC. (CH) 2017-06-22 US disclosed
US-20160176132-A1 REUSABLE LENS MOLDS AND METHODS OF USE THEREOF ALCON INC. (CH) 2016-06-23 US disclosed
US-20160176134-A1 REUSABLE LENS MOLDS AND METHODS OF USE THEREOF ALCON INC. (CH) 2016-06-23 US disclosed