SCHEMBL8466019

SCHEMBL8466019

CC(=CCCC[Si](O[Si](O[Si](C)(C)C)(O[Si](C)(C)C)O[Si](C)(C)C)(O[Si](O[Si](C)(C)C)(O[Si](C)(C)C)O[Si](C)(C)C)O[Si](O[Si](C)(C)C)(O[Si](C)(C)C)O[Si](C)(C)C)C(=O)O

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TBXAS1 P24557 1/20 0.32
CD81 P60033 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL809437 0.92 TBXAS1 (0.33) TBXAS1CD81
SCHEMBL400292 0.92 TBXAS1 (0.33) TBXAS1CD81
SCHEMBL1803466 0.88 TBXAS1 (0.32) TBXAS1CD81
SCHEMBL1802297 0.86 TBXAS1 (0.31) TBXAS1
Acrylamide SCHEMBL17840598 0.82 ALDH1A1 (0.31)
SCHEMBL2474722 0.82 TDP1 (0.33)
SCHEMBL1581278 0.82 TBXAS1 (0.33) TBXAS1CD81
SCHEMBL442701 0.82 TBXAS1 (0.33) TBXAS1CD81
SCHEMBL403240 0.82 CD81 (0.33) CD81
SCHEMBL20597263 0.80 TBXAS1 (0.31) TBXAS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0793541-B1 NCO-TERMINATED VINYL TELOMERS NOVARTIS AG (CH) 1999-09-22 EP disclosed
EP-0800657-B1 POLYMERS BASED ON BLOCK COPOLYMERS NOVARTIS AG (CH) 1998-11-25 EP disclosed
EP-0455587-B1 New polymers and hard gas-permeable contact lenses made therefrom CIBA GEIGY AG (CH) 1995-07-19 EP disclosed
EP-0538188-A1 Propellane-containing copolymers and contact lenses thereof CIBA-GEIGY AG (CH) 1993-04-21 EP disclosed
EP-0455587-A1 New polymers and hard gas-permeable contact lenses made therefrom CIBA-GEIGY AG (CH) 1991-11-06 EP disclosed