Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Docusate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.32 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
| ▸ | MMP14 | P50281 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Docusate SCHEMBL1282782 | 0.99 | RECQL (0.72) | RECQLCYP3A4TSHRTDP1ATM | |
| Docusate SCHEMBL6932639 | 0.98 | RECQL (0.71) | RECQLCYP3A4TSHRTDP1ATM | |
| Docusate SCHEMBL11434516 | 0.98 | RECQL (0.71) | RECQLCYP3A4TSHRTDP1ATM | |
| Docusate SCHEMBL22231584 | 0.98 | RECQL (0.71) | RECQLCYP3A4TSHRTDP1ATM | |
| Docusate SCHEMBL727271 | 0.98 | RECQL (0.71) | RECQLCYP3A4TSHRTDP1ATM | |
| Docusate SCHEMBL723749 | 0.98 | RECQL (0.71) | RECQLCYP3A4TSHRTDP1ATM | |
| Docusate SCHEMBL19022251 | 0.98 | RECQL (0.71) | RECQLCYP3A4TSHRTDP1ATM | |
| Docusate SCHEMBL2371693 | 0.95 | RECQL (0.79) | RECQLCYP3A4TSHRTDP1ATM | |
| Docusate SCHEMBL22245572 | 0.94 | RECQL (0.65) | RECQLCYP3A4TSHRTDP1ATM | |
| Docusate SCHEMBL6538331 | 0.91 | RECQL (0.69) | RECQLCYP3A4TSHRTDP1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3398223-A1 | CERAMIC-POLYMER COMPOSITE ELECTROLYTES FOR LITHIUM POLYMER BATTERIES | Seeo, Inc (US) | 2018-11-07 | — | — | EP | claimed |
| US-20170187063-A1 | CERAMIC-POLYMER COMPOSITE ELECTROLYTES FOR LITHIUM POLYMER BATTERIES | SEEO, INC | 2017-06-29 | — | — | US | claimed |
| EP-4378999-A1 | THERMOPLASTIC RESIN COMPOSITION, METHOD FOR PRODUCING SAME, AND MOLDED ARTICLE INCLUDING SAME | LG Chem, Ltd. (KR) | 2024-06-05 | — | — | EP | disclosed |
| WO-2024085369-A1 | THERMOPLASTIC RESIN COMPOSITION, METHOD FOR PRODUCING SAME, AND MOLDED ARTICLE INCLUDING SAME | (주) 엘지화학 | 2024-04-25 | — | — | WO | disclosed |
| EP-4339244-A1 | THERMOPLASTIC RESIN COMPOSITION, METHOD FOR PREPARING SAME, AND MOLDED PRODUCT MANUFACTURED THEREFROM | LG Chem, Ltd. (KR) | 2024-03-20 | — | — | EP | disclosed |
| EP-4339243-A1 | THERMOPLASTIC RESIN COMPOSITION, PREPARATION METHOD THEREFOR, AND MOLDED PRODUCT MANUFACTURED THEREFROM | LG Chem, Ltd. (KR) | 2024-03-20 | — | — | EP | disclosed |
| EP-4332163-A1 | THERMOPLASTIC RESIN COMPOSITION, METHOD FOR PRODUCING SAME, AND MOLDED ARTICLE PRODUCED THEREFROM | LG Chem, Ltd. (KR) | 2024-03-06 | — | — | EP | disclosed |
| CN-115279807-B | Method for preparing vinyl cyanide compound-conjugated diene rubber-aromatic vinyl compound graft copolymer and method for preparing thermoplastic resin composition comprising the same | 株式会社LG化学 | 2024-01-30 | — | — | CN | disclosed |
| WO-2023243910-A1 | THERMOPLASTIC RESIN COMPOSITION, METHOD FOR PRODUCING SAME, AND MOLDED ARTICLE PRODUCED THEREFROM | (주) 엘지화학 | 2023-12-21 | — | — | WO | disclosed |
| WO-2023243909-A1 | THERMOPLASTIC RESIN COMPOSITION, PREPARATION METHOD THEREFOR, AND MOLDED PRODUCT MANUFACTURED THEREFROM | (주) 엘지화학 | 2023-12-21 | — | — | WO | disclosed |
| WO-2023243908-A1 | THERMOPLASTIC RESIN COMPOSITION, METHOD FOR PREPARING SAME, AND MOLDED PRODUCT MANUFACTURED THEREFROM | (주) 엘지화학 | 2023-12-21 | — | — | WO | disclosed |
| EP-3398223-A1 | CERAMIC-POLYMER COMPOSITE ELECTROLYTES FOR LITHIUM POLYMER BATTERIES | Seeo, Inc (US) | 2018-11-07 | — | — | EP | disclosed |
| WO-2018178721-A1 | METHOD FOR PRODUCING A LIQUID COMPOSITION | THE UNIVERSITY OF LIVERPOOL (GB) | 2018-10-04 | — | — | WO | disclosed |
| US-9845538-B2 | Etching agent, etching method and etching agent preparation liquid | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2017-12-19 | — | — | US | disclosed |
| US-20170349688-A1 | WEATHER-RESISTANT THERMOPLASTIC RESIN, THERMOPLASTIC RESIN COMPOSITION CONTAINING THE SAME, AND METHOD OF PREPARING THERMOPLASTIC | LG CHEM, LTD. (KR) | 2017-12-07 | — | — | US | disclosed |
| EP-3205689-A1 | WEATHER RESISTANT THERMOPLASTIC RESIN, THERMOPLASTIC RESIN COMPOSITION CONTAINING SAME, AND METHOD FOR PREPARING COMPOSITION | LG Chem, Ltd. (KR) | 2017-08-16 | — | — | EP | disclosed |
| US-20170187063-A1 | CERAMIC-POLYMER COMPOSITE ELECTROLYTES FOR LITHIUM POLYMER BATTERIES | SEEO, INC | 2017-06-29 | — | — | US | disclosed |
| US-20160177457-A1 | ETCHING AGENT, ETCHING METHOD AND ETCHING AGENT PREPARATION LIQUID | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2016-06-23 | — | — | US | disclosed |
| CN-1232551-C | Method for preparing weather-resistant thermoplastic resin | LG CHENMICAL LTD (KR) | 2005-12-21 | — | — | CN | disclosed |
| CN-1452639-A | Methods for preparing of weatherability thermoplastic resin | LG CHEN LTD (KR) | 2003-10-29 | — | — | CN | disclosed |