Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | MC4R | P32245 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | STAT3 | P40763 | 1/20 | 0.31 |
| ▸ | STAT1 | P42224 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17844095 | 0.78 | CCNE1 (0.34) | MALT1LRRK2MCL1P2RX7 | |
| SCHEMBL17110772 | 0.73 | NPC1 (0.49) | MALT1MCL1KDM4EHTTMEN1 | |
| SCHEMBL17726166 | 0.65 | KDM4E (0.32) | MCL1KDM4ECASP1CASP7HSD17B10 | |
| SCHEMBL30907391 | 0.65 | KDM4E (0.38) | MC4RKDM4ECASP1CASP7HSD17B10 | |
| SCHEMBL9930969 | 0.65 | COMT (0.54) | RORC | |
| SCHEMBL15011218 | 0.65 | SCN9A (0.41) | MCL1MC4RKDM4ENPC1ALDH1A1 | |
| SCHEMBL3728805 | 0.65 | LRRK2 (0.41) | MALT1LRRK2MCL1MC4RNPC1 | |
| SCHEMBL25328877 | 0.62 | TRPA1 (0.44) | MCL1KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL9953904 | 0.62 | HSD11B1 (0.39) | LRRK2MCL1RORC | |
| SCHEMBL28343831 | 0.62 | MC4R (0.53) | MC4RKDM4EHTTALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3233851-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | Syngenta Participations AG (CH) | 2017-10-25 | — | — | EP | disclosed |
| WO-2016096584-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-06-23 | — | — | WO | disclosed |