Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 4/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.32 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | IL1B | P01584 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9952924 | 0.84 | HTT (0.33) | LRRK2RORCOPRK1DPP4 | |
| SCHEMBL9952956 | 0.79 | KMT2A (0.36) | HSD11B1LRRK2KDM4COPRK1TRPM5 | |
| SCHEMBL9930969 | 0.71 | COMT (0.54) | RORCKDM4CKCNH2 | |
| SCHEMBL9951982 | 0.70 | NPC1 (0.32) | LRRK2OPRK1 | |
| SCHEMBL9952037 | 0.69 | OPRK1 (0.32) | OPRK1 | |
| SCHEMBL12320160 | 0.69 | SMN1; SMN2 (0.52) | HSD11B1LRRK2 | |
| SCHEMBL14960646 | 0.68 | TGFBR1 (0.50) | LRRK2TGFBR1KCNH2 | |
| SCHEMBL27759199 | 0.67 | LPO (0.44) | — | |
| SCHEMBL24575964 | 0.67 | MYC (0.40) | LRRK2DPP4 | |
| SCHEMBL27589731 | 0.67 | BRD4 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103261170-B | Fused heterocyclic compounds and their use for pest control | 住友化学株式会社 | 2016-08-24 | — | — | CN | disclosed |
| EP-2655337-A1 | FUSED HETEROCYCLIC COMPOUND AND USE FOR PEST CONTROL THEREOF | Sumitomo Chemical Company Limited (JP) | 2013-10-30 | — | — | EP | disclosed |
| CN-103261170-A | Fused heterocyclic compounds and their use for pest control | SUMITOMO CHEMICAL CO | 2013-08-21 | — | — | CN | disclosed |
| WO-2012086848-A1 | FUSED HETEROCYCLIC COMPOUND AND USE FOR PEST CONTROL THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-06-28 | — | — | WO | disclosed |