Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | STAT1 | P42224 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SOAT1 | P35610 | 4/20 | 0.36 |
| ▸ | SOAT2 | O75908 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.35 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5184388 | 0.90 | FAAH (0.47) | FAAHMGLLSLC2A1ALDH1A1NPC1 | |
| SCHEMBL17844132 | 0.89 | FAAH (0.39) | FAAHMGLLALDH1A1RAB9AADORA2B | |
| SCHEMBL5186704 | 0.86 | FAAH (0.38) | FAAHMGLLSLC2A1ALDH1A1NPC1 | |
| SCHEMBL17844161 | 0.78 | FAAH (0.44) | FAAHMGLLALDH1A1NPC1MAPT | |
| SCHEMBL17844198 | 0.78 | MEN1 (0.48) | FAAHMGLLALDH1A1MAPTHTT | |
| SCHEMBL17844070 | 0.76 | FAAH (0.40) | FAAHMGLLALDH1A1NPC1RAB9A | |
| SCHEMBL5186011 | 0.75 | ALDH1A1 (0.48) | FAAHMGLLALDH1A1MAPTHTT | |
| SCHEMBL17844060 | 0.74 | KDM4E (0.48) | SLC2A1ALDH1A1NPC1MAPTRAB9A | |
| SCHEMBL17844174 | 0.74 | FAAH (0.40) | FAAHMGLLALDH1A1NPC1MAPT | |
| SCHEMBL17844158 | 0.74 | GAA (0.43) | ALDH1A1NPC1MAPTRAB9AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016100619-A2 | TREATMENT AND DIAGNOSIS OF CANCER | RGENIX, INC. (US) | 2016-06-23 | — | — | WO | disclosed |